SETD2 抗体 (N-Term)
(1 reference)-
- 抗原 See all SETD2 抗体
- SETD2 (SET Domain Containing 2 (SETD2))
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抗原表位
- AA 21-50, N-Term
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适用
- 人
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This SETD2 antibody is un-conjugated
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应用范围
- Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
- 预测反应
- M
- 纯化方法
- This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.
- 免疫原
- This SET2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 21~50 amino acids from the N-terminal region of human SET2.
- 克隆位点
- RB2780
- 亚型
- Ig Fraction
- Top Product
- Discover our top product SETD2 Primary Antibody
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anti-SET Domain Containing 2 (SETD2) (AA 803-1103) antibody
SETD2 适用: 人 WB, IF 宿主: 兔 Polyclonal unconjugated
anti-SET Domain Containing 2 (SETD2) (AA 2054-2245) antibodySETD2 适用: 人 ELISA, FACS 宿主: 小鼠 Monoclonal 4G11E6 unconjugated
anti-SET Domain Containing 2 (SETD2) (N-Term) antibodySETD2 适用: 人, 大鼠, 犬 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-SET Domain Containing 2 (SETD2) (N-Term) antibodySETD2 适用: 人, 小鼠, 大鼠, 犬, 马, Cow WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-SET Domain Containing 2 (SETD2) antibodySETD2 适用: 人, 小鼠 IHC, ELISA 宿主: 兔 Polyclonal unconjugated
anti-SET Domain Containing 2 (SETD2) (AA 323-372) antibodySETD2 适用: 人, 小鼠, 大鼠, 犬, 马, Cow WB, IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated
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- 应用备注
- IHC-P: 1:50~100
- 限制
- 仅限研究用
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- 状态
- Liquid
- 缓冲液
- Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- 4 °C,-20 °C
- 有效期
- 6 months
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: "Organization of chromatin and histone modifications at a transcription site." in: The Journal of cell biology, Vol. 177, Issue 6, pp. 957-67, (2007) (PubMed).
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: "Organization of chromatin and histone modifications at a transcription site." in: The Journal of cell biology, Vol. 177, Issue 6, pp. 957-67, (2007) (PubMed).
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- 抗原
- SETD2 (SET Domain Containing 2 (SETD2))
- 别名
- SET2 (SETD2 产品)
- 别名
- Kif9 antibody, HBP231 antibody, HIF-1 antibody, HIP-1 antibody, HYPB antibody, KMT3A antibody, SET2 antibody, p231HBP antibody, SET domain containing 2 antibody, Setd2 antibody, SETD2 antibody
- 背景
- SET2 is a histone methyltransferase that methylates 'Lys-36' of histone H3. H3 'Lys-36' methylation represents a specific tag for epigenetic transcriptional activation. This protein probably plays a role in chromatin structure modulation during elongation via its interaction with hyperphosphorylated POLR2A. SET2 binds DNA at promoters, and may act as a transcription activator. SET2 binds to the promoters of adenovirus 12 E1A gene in case of infection, possibly leading to regulate its expression. Huntington's disease (HD), a neurodegenerative disorder characterized by loss of striatal neurons, is caused by an expansion of a polyglutamine tract in the HD protein huntingtin. SET2 belongs to a class of huntingtin interacting proteins characterized by WW motifs.
- 分子量
- 287597
- NCBI登录号
- NP_054878
- UniProt
- Q9BYW2
- 途径
- Tube Formation
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