This antibody is purified through a protein A column, followed by peptide affinity purification.
免疫原
This FKBP1A antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between 34-68 amino acids from the Central region of human FKBP1A.
Keeps in an inactive conformation TGFBR1, the TGF-beta type I serine/threonine kinase receptor, preventing TGF-beta receptor activation in absence of ligand. Recruites SMAD7 to ACVR1B which prevents the association of SMAD2 and SMAD3 with the activin receptor complex, thereby blocking the activin signal. May modulate the RYR1 calcium channel activity. PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides.