This antibody is purified through a protein A column, followed by peptide affinity purification.
免疫原
This DEDD2 antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between 162-193 amino acids from the Central region of human DEDD2.
May play a critical role in death receptor-induced apoptosis and may target CASP8 and CASP10 to the nucleus. May regulate degradation of intermediate filaments during apoptosis. May play a role in the general transcription machinery in the nucleus and might be an important regulator of the activity of GTF3C3.