This antibody is purified through a protein A column, followed by peptide affinity purification.
免疫原
This CLIC2 antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between 105-137 amino acids from the Central region of human CLIC2.
Can insert into membranes and form chloride ion channels. Channel activity depends on the pH . Membrane insertion seems to be redox-regulated and may occur only under oxydizing conditions. Modulates the activity of RYR2 and inhibits calcium influx.