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- 抗原 See all CHD5 抗体
- CHD5 (Chromodomain Helicase DNA Binding Protein 5 (CHD5))
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抗原表位
- AA 64-98
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适用
- 人
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This CHD5 antibody is un-conjugated
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应用范围
- Western Blotting (WB)
- 纯化方法
- This antibody is purified through a protein A column, followed by peptide affinity purification.
- 免疫原
- This CHD5 antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between 64-98 amino acids from human CHD5.
- 克隆位点
- RB54755
- 亚型
- Ig Fraction
- Top Product
- Discover our top product CHD5 Primary Antibody
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anti-Chromodomain Helicase DNA Binding Protein 5 (CHD5) (AA 1600-1699) antibody
CHD5 适用: 人 ELISA, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Chromodomain Helicase DNA Binding Protein 5 (CHD5) (C-Term) antibodyCHD5 适用: 人 ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Chromodomain Helicase DNA Binding Protein 5 (CHD5) (C-Term) antibodyCHD5 适用: 人, 小鼠 WB, IF, ICC 宿主: 大鼠 Monoclonal 5A10 unconjugated
anti-Chromodomain Helicase DNA Binding Protein 5 (CHD5) (Internal Region) antibodyCHD5 适用: 人 ELISA, WB, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-Chromodomain Helicase DNA Binding Protein 5 (CHD5) (Internal Region) antibodyVerified CHD5 适用: 人 ELISA, IF, FACS 宿主: 山羊 Polyclonal unconjugated
anti-Chromodomain Helicase DNA Binding Protein 5 (CHD5) (AA 712-896) antibodyCHD5 适用: 人 WB, IHC, ICC 宿主: 兔 Polyclonal unconjugated
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- 应用备注
- WB: 1:2000
- 限制
- 仅限研究用
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- 状态
- Liquid
- 缓冲液
- Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- 4 °C,-20 °C
- 有效期
- 6 months
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- 抗原
- CHD5 (Chromodomain Helicase DNA Binding Protein 5 (CHD5))
- 别名
- CHD5 (CHD5 产品)
- 别名
- CHD-5 antibody, 4930532L22Rik antibody, AW060752 antibody, B230399N07Rik antibody, CHD5 antibody, chromodomain helicase DNA binding protein 5 antibody, potassium voltage-gated channel subfamily A regulatory beta subunit 2 antibody, CHD5 antibody, Chd5 antibody, chd5 antibody, KCNAB2 antibody
- 背景
- Chromatin-remodeling protein that binds DNA through histones and regulates gene transcription. May specifically recognize and bind trimethylated 'Lys-27' (H3K27me3) and non- methylated 'Lys-4' of histone H3. Plays a role in the development of the nervous system by activating the expression of genes promoting neuron terminal differentiation. In parallel, it may also positively regulate the trimethylation of histone H3 at 'Lys- 27' thereby specifically repressing genes that promote the differentiation into non-neuronal cell lineages. Tumor suppressor, it regulates the expression of genes involved in cell proliferation and differentiation. Downstream activated genes may include CDKN2A that positively regulates the p53/TP53 pathway, which in turn, prevents cell proliferation. In spermatogenesis, it probably regulates histone hyperacetylation and the replacement of histones by transition proteins in chromatin, a crucial step in the condensation of spermatid chromatin and the production of functional spermatozoa.
- 分子量
- 223050
- UniProt
- Q8TDI0
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