This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.
免疫原
This Zebrafish tead1b antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 324-352 amino acids from the C-terminal region of Zebrafish tead1b.
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背景
TEAD1 binds specifically and cooperatively to the SPH and GT-IIC enhansons (5'-GTGGAATGT-3') and activates transcription in vivo in a cell-specific manner. The activation function appears to be mediated by a limiting cell-specific transcriptional intermediary factor (TIF). It is involved in cardiac development and binds to the M-CAT motif.