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- 抗原 See all NEIL3 抗体
- NEIL3 (Nei Endonuclease VIII-Like 3 (NEIL3))
- 适用
- 人, 小鼠, 大鼠
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This NEIL3 antibody is un-conjugated
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应用范围
- Western Blotting (WB)
- 免疫原
- synthetic peptide
- Top Product
- Discover our top product NEIL3 Primary Antibody
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anti-Nei Endonuclease VIII-Like 3 (NEIL3) (AA 2-187) antibody
NEIL3 适用: 小鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Nei Endonuclease VIII-Like 3 (NEIL3) (C-Term) antibodyNEIL3 适用: 人, 小鼠 WB, ELISA, ICC, IF 宿主: 兔 Polyclonal unconjugated
anti-Nei Endonuclease VIII-Like 3 (NEIL3) (C-Term) antibodyNEIL3 适用: 人 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Nei Endonuclease VIII-Like 3 (NEIL3) (AA 292-320) antibodyNEIL3 适用: 人 WB 宿主: 兔 Polyclonal RB40413 unconjugated
anti-Nei Endonuclease VIII-Like 3 (NEIL3) (C-Term) antibodyNEIL3 适用: 人, 小鼠 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Nei Endonuclease VIII-Like 3 (NEIL3) antibodyNEIL3 适用: 人 DB 宿主: 小鼠 Monoclonal 2627C1b unconjugated
anti-Nei Endonuclease VIII-Like 3 (NEIL3) (C-Term) antibodyNEIL3 适用: 人, 小鼠, 大鼠 WB, IHC, IP 宿主: 兔 Polyclonal unconjugated
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- 应用备注
- WB: 1:1000
- 限制
- 仅限研究用
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- 状态
- Liquid
- 储存条件
- 4 °C,-20 °C
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- 抗原
- NEIL3 (Nei Endonuclease VIII-Like 3 (NEIL3))
- 别名
- NEIL3 (NEIL3 产品)
- 背景
- DNA glycosylase which prefers single-stranded DNA (ssDNA), or partially ssDNA structures such as bubble and fork structures, to double-stranded DNA (dsDNA). In vitro, displays strong glycosylase activity towards the hydantoin lesions spiroiminodihydantoin (Sp) and guanidinohydantoin (Gh) in both ssDNA and dsDNA, also recognizes FapyA, FapyG, 5-OHU, 5-OHC, 5- OHMH, Tg and 8-oxoA lesions in ssDNA. No activity on 8-oxoG detected. Also shows weak DNA-(apurinic or apyrimidinic site) lyase activity. In vivo, appears to be the primary enzyme involved in removing Sp and Gh from ssDNA in neonatal tissues. Seems to be an important facilitator of cell proliferation in certain populations, for example neural stem/progenitor cells and tumor cells, suggesting a role in replication-associated DNA repair.
- UniProt
- Q8TAT5
- 途径
- DNA Damage Repair
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