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- 抗原 See all PTEN 抗体
- PTEN (Phosphatase and Tensin Homolog (PTEN))
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抗原表位
- pTyr315
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适用
- 人
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This PTEN antibody is un-conjugated
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应用范围
- Dot Blot (DB)
- 预测反应
- M
- 纯化方法
- This antibody is purified through a protein A column, followed by peptide affinity purification.
- 免疫原
- This PTEN Antibody is generated from rabbits immunized with a KLH conjugated synthetic phosphopeptide corresponding to amino acid residues surrounding Y315 of human PTEN.
- 克隆位点
- RB30516
- 亚型
- Ig Fraction
- Top Product
- Discover our top product PTEN Primary Antibody
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anti-Phosphatase and Tensin Homolog (PTEN) (AA 69-104), (N-Term) antibody
PTEN 适用: 人 WB, IF, IHC (p) 宿主: 兔 Polyclonal RB05082 unconjugated
anti-Phosphatase and Tensin Homolog (PTEN) (AA 69-104) antibodyPTEN 适用: 人 WB, ELISA, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Phosphatase and Tensin Homolog (PTEN) (AA 2-403) antibodyPTEN 适用: 人 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Phosphatase and Tensin Homolog (PTEN) (AA 264-295), (C-Term) antibodyPTEN 适用: 人 WB, IF, IHC (p) 宿主: 兔 Polyclonal RB5083 unconjugated
anti-Phosphatase and Tensin Homolog (PTEN) (AA 306-335) antibodyPTEN 适用: 人 WB, ELISA, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Phosphatase and Tensin Homolog (PTEN) (AA 264-295) antibodyPTEN 适用: 人 WB, ELISA, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Phosphatase and Tensin Homolog (PTEN) (acLys402) antibodyPTEN 适用: 人 WB, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Phosphatase and Tensin Homolog (PTEN) (AA 363-392) antibodyPTEN 适用: 人 WB 宿主: 兔 Polyclonal RB39439 unconjugated
anti-Phosphatase and Tensin Homolog (PTEN) (C-Term) antibodyPTEN 适用: 人, 小鼠, 大鼠, 犬, Pig, 猴 WB, IHC, IF, IC 宿主: 兔 Polyclonal unconjugated
anti-Phosphatase and Tensin Homolog (PTEN) (C-Term), (pSer380), (pThr382), (pThr383) antibodyPTEN 适用: 人, 小鼠, 大鼠, 犬, 斑马鱼 WB, IHC, IF, IP, IC 宿主: 兔 Polyclonal unconjugated
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- 应用备注
- DB: 1:500
- 限制
- 仅限研究用
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- 状态
- Liquid
- 缓冲液
- Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- 4 °C,-20 °C
- 有效期
- 6 months
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- 抗原
- PTEN (Phosphatase and Tensin Homolog (PTEN))
- 别名
- PTEN (PTEN 产品)
- 别名
- 10q23del antibody, BZS antibody, CWS1 antibody, DEC antibody, GLM2 antibody, MHAM antibody, MMAC1 antibody, PTEN1 antibody, TEP1 antibody, 2310035O07Rik antibody, A130070J02Rik antibody, AI463227 antibody, B430203M17Rik antibody, Mmac antibody, PTENP1 antibody, wu:fc52g04 antibody, zgc:73086 antibody, fa11a08 antibody, fb73f10 antibody, fc83f12 antibody, fd16b10 antibody, fk90e11 antibody, pten antibody, si:bz1g13.4 antibody, wu:fa11a08 antibody, wu:fb73f10 antibody, wu:fc83f12 antibody, wu:fd16b10 antibody, wu:fk90e11 antibody, phosphatase and tensin homolog antibody, phosphatase and tensin homolog L homeolog antibody, phosphatase and tensin homolog A antibody, phosphatase and tensin homolog B antibody, PTEN antibody, Pten antibody, pten.L antibody, ptena antibody, ptenb antibody
- 背景
- This gene was identified as a tumor suppressor that is mutated in a large number of cancers at high frequency. The protein encoded this gene is a phosphatidylinositol-3,4,5-trisphosphate 3-phosphatase. It contains a tensin like domain as well as a catalytic domain similar to that of the dual specificity protein tyrosine phosphatases. Unlike most of the protein tyrosine phosphatases, this protein preferentially dephosphorylates phosphoinositide substrates. It negatively regulates intracellular levels of phosphatidylinositol-3,4,5-trisphosphate in cells and functions as a tumor suppressor by negatively regulating AKT/PKB signaling pathway.
- 分子量
- 47166
- NCBI登录号
- NP_000305
- UniProt
- P60484
- 途径
- TCR Signaling, Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Inositol Metabolic Process, Synaptic Membrane, Regulation of Cell Size, Autophagy, Platelet-derived growth Factor Receptor Signaling, Signaling of Hepatocyte Growth Factor Receptor, BCR Signaling
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