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PDGFRB 抗体 (pTyr579)

PDGFRB 适用: 人 IHC (p) 宿主: 兔 Polyclonal RB5692 unconjugated
产品编号 ABIN6241032
发货至: 中国
  • 抗原 See all PDGFRB 抗体
    PDGFRB (Platelet Derived Growth Factor Receptor beta (PDGFRB))
    抗原表位
    • 25
    • 19
    • 19
    • 15
    • 15
    • 8
    • 7
    • 7
    • 6
    • 5
    • 5
    • 5
    • 5
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    pTyr579
    适用
    • 192
    • 72
    • 69
    • 4
    • 4
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    宿主
    • 170
    • 25
    • 3
    • 2
    克隆类型
    • 158
    • 42
    多克隆
    标记
    • 105
    • 9
    • 8
    • 7
    • 4
    • 4
    • 4
    • 4
    • 4
    • 4
    • 4
    • 4
    • 4
    • 4
    • 4
    • 4
    • 4
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 1
    This PDGFRB antibody is un-conjugated
    应用范围
    • 150
    • 70
    • 54
    • 53
    • 45
    • 30
    • 28
    • 19
    • 17
    • 10
    • 10
    • 4
    • 2
    • 2
    • 1
    Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
    预测反应
    C, Zf, M, Rat, X
    纯化方法
    This antibody is purified through a protein A column, followed by peptide affinity purification.
    免疫原
    This Phospho-PDGFR-Y579 antibody is generated from rabbits immunized with a KLH conjugated synthetic phosphopeptide corresponding to amino acid residues surrounding Y579 of human PDGFR.
    克隆位点
    RB5692
    亚型
    Ig Fraction
    Top Product
    Discover our top product PDGFRB Primary Antibody
  • 应用备注
    IHC-P: 1:50~100
    限制
    仅限研究用
  • 状态
    Liquid
    缓冲液
    Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    4 °C,-20 °C
    有效期
    6 months
  • Guo, Reinitz, Youssef, Hong, Nathanson, Akhavan, Kuga, Amzajerdi, Soto, Zhu, Babic, Tanaka, Dang, Iwanami, Gini, Dejesus, Lisiero, Huang, Prins, Wen, Robins, Prados, Deangelis, Mellinghoff, Mehta et al.: "An LXR agonist promotes glioblastoma cell death through inhibition of an EGFR/AKT/SREBP-1/LDLR-dependent pathway. ..." in: Cancer discovery, Vol. 1, Issue 5, pp. 442-56, (2012) (PubMed).

  • 抗原
    PDGFRB (Platelet Derived Growth Factor Receptor beta (PDGFRB))
    别名
    PDGFR (PDGFRB 产品)
    背景
    PDGFR is a cell surface tyrosine kinase receptor for members of the platelet-derived growth factor family. These growth factors are mitogens for cells of mesenchymal origin. The identity of the growth factor bound to a receptor monomer determines whether the functional receptor is a homodimer or a heterodimer, composed of both platelet-derived growth factor receptor alpha and beta polypeptides. The gene for this protein is flanked on chromosome 5 by the genes for granulocyte-macrophage colony-stimulating factor and macrophage-colony stimulating factor receptor, all three genes may be implicated in the 5-q syndrome. A translocation between chromosomes 5 and 12, that fuses this gene to that of the translocation, ETS, leukemia gene, results in chronic myelomonocytic leukemia.
    分子量
    123968
    NCBI登录号
    NP_002600
    UniProt
    P09619
    途径
    Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway, Inositol Metabolic Process, Glycosaminoglycan Metabolic Process, Smooth Muscle Cell Migration, Platelet-derived growth Factor Receptor Signaling
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