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MAPK6 抗体 (pSer189)

Name: MAPK6 抗体 (pSer189)
SKU: ABIN6241031
Availability: OutOfStock

MAPK6 适用: 人 IHC (p) 宿主: 兔 Polyclonal RB5800 unconjugated

Formalin-fixed and paraffin-embedded human cancer tissue reacted with the primary antibody, which was peroxidase-conjugated to the secondary antibody, followed by AEC staining. (MAPK6 抗体 (pSer189))

IHC (p)

1 image

(5 references)

产品编号 ABIN6241031

发货至: 中国

Datasheet as PDF

抗原 See all MAPK6 抗体

MAPK6 (Mitogen-Activated Protein Kinase 6 (MAPK6))
抗原表位
17

15

5

4

2

2

2

2

2

2

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1
pSer189
适用
56

47

28

5

3

3

3

3

3

3

2

2

1

1

1

1
人
宿主
62

6

3

1
兔
Compatible Secondaries
克隆类型
67

5
多克隆
标记
39

6

5

3

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1
This MAPK6 antibody is un-conjugated
应用范围
51

36

19

14

13

11

8

7

3

3

1

1

1
Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

预测反应

C, M, Rat

纯化方法

This antibody is purified through a protein A column, followed by peptide affinity purification.

免疫原

This Phospho-ERK3-S189 antibody is generated from rabbits immunized with a KLH conjugated synthetic phosphopeptide corresponding to amino acid residues surrounding S189 of human ERK3.

克隆位点

RB5800

亚型

Ig Fraction

Top Product

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MAPK6 适用: 人 WB, ELISA, IF 宿主: 小鼠 Monoclonal 4C11 unconjugated

anti-Mitogen-Activated Protein Kinase 6 (MAPK6) (AA 612-721) antibody
MAPK6 适用: 人 WB, ELISA, IF, RNAi 宿主: 小鼠 Monoclonal 1G6 unconjugated

anti-Mitogen-Activated Protein Kinase 6 (MAPK6) antibody
MAPK6 适用: 人 ELISA, FACS 宿主: 小鼠 Monoclonal 4E8 unconjugated

anti-Mitogen-Activated Protein Kinase 6 (MAPK6) (AA 1-316) antibody
MAPK6 适用: 人 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated

anti-Mitogen-Activated Protein Kinase 6 (MAPK6) antibody
MAPK6 适用: 人, 小鼠, 大鼠 ELISA, IHC 宿主: 兔 Polyclonal unconjugated

anti-Mitogen-Activated Protein Kinase 6 (MAPK6) (AA 372-721) antibody
KO Validated MAPK6 适用: 人 WB, IHC, IF 宿主: 兔 Polyclonal unconjugated

anti-Mitogen-Activated Protein Kinase 6 (MAPK6) (Center) antibody
MAPK6 适用: 人, 小鼠, Cow, 小鸡, 猴 WB, IHC, IF, IC 宿主: 兔 Polyclonal unconjugated

anti-Mitogen-Activated Protein Kinase 6 (MAPK6) (AA 21-120) antibody
MAPK6 适用: 小鼠 WB, ELISA, IF (cc), IF (p), IHC (p), ICC, IHC (fro) 宿主: 兔 Polyclonal unconjugated

anti-Mitogen-Activated Protein Kinase 6 (MAPK6) (AA 383-712) antibody
MAPK6 适用: 人 ELISA, IHC 宿主: 兔 Polyclonal unconjugated

anti-Mitogen-Activated Protein Kinase 6 (MAPK6) (AA 692-721), (C-Term) antibody
MAPK6 适用: 人 WB 宿主: 兔 Polyclonal RB0915 unconjugated

应用备注

IHC-P: 1:50~100

限制

仅限研究用
状态

Liquid

缓冲液

Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

储存液

Sodium azide

注意事项

This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

储存条件

4 °C,-20 °C

有效期

6 months
Wang, Kong, Lin, Li, Izumiya, Ding, Zhang, Hu, Yang, Gao, Lam, Li: "A versatile nanoplatform for synergistic combination therapy to treat human esophageal cancer." in: Acta pharmacologica Sinica, Vol. 38, Issue 6, pp. 931-942, (2018) (PubMed).

Perander, Al-Mahdi, Jensen, Nunn, Kildalsen, Johansen, Gabrielsen, Keyse, Seternes: "Regulation of atypical MAP kinases ERK3 and ERK4 by the phosphatase DUSP2." in: Scientific reports, Vol. 7, pp. 43471, (2017) (PubMed).

De la Mota-Peynado, Chernoff, Beeser: "Identification of the atypical MAPK Erk3 as a novel substrate for p21-activated kinase (Pak) activity." in: The Journal of biological chemistry, Vol. 286, Issue 15, pp. 13603-11, (2011) (PubMed).

Purcell, Wilkins, York, Saba-El-Leil, Meloche, Robbins, Molkentin: "Genetic inhibition of cardiac ERK1/2 promotes stress-induced apoptosis and heart failure but has no effect on hypertrophy in vivo." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 104, Issue 35, pp. 14074-9, (2007) (PubMed).

Sakai, Yamauchi, Kawano: "[Measurement of internal voids in impression material using a digital image analyzer. Part 1. Investigation of the measurement system of a digital image analyzer]." in: Nihon Hotetsu Shika Gakkai zasshi, Vol. 32, Issue 1, pp. 28-36, (1989) (PubMed).
抗原

MAPK6 (Mitogen-Activated Protein Kinase 6 (MAPK6))

别名

ERK3 (MAPK6 产品)

别名

ERK3 antibody, HsT17250 antibody, PRKM6 antibody, p97MAPK antibody, 2610021I23Rik antibody, D130053K17Rik antibody, Erk3 antibody, Mapk4 antibody, Mapk63 antibody, Prkm4 antibody, Prkm6 antibody, ATMAPK6 antibody, ATMPK6 antibody, F18O19.10 antibody, MAP KINASE 6 antibody, MAP kinase 6 antibody, MAPK6 antibody, SUSERK3 antibody, erk3 antibody, p97mapk antibody, si:ch211-235f12.1 antibody, mitogen-activated protein kinase 6 antibody, MAP kinase 6 antibody, MAPK6 antibody, Mapk6 antibody, MPK6 antibody, mapk6 antibody

背景

ERK3 is a member of the Ser/Thr protein kinase family, and is most closely related to mitogen-activated protein kinases (MAP kinases). MAP kinases also known as extracellular signal-regulated kinases (ERKs), are activated through protein phosphorylation cascades and act as integration points for multiple biochemical signals. This kinase is localized in the nucleus, and has been reported to be activated in fibroblasts upon treatment with serum or phorbol esters.

分子量

82681

NCBI登录号

NP_002739

UniProt

Q16659

途径

MAPK Pathway, Neurotrophin Signaling Pathway, Regulation of Muscle Cell Differentiation, Hepatitis C