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CD200 抗体

This anti-CD200 antibody is a 小鼠 单克隆 antibody detecting CD200 in FACS, IHC (fro) 和 IHC (p). Suitable for 人.
产品编号 ABIN6240832
发货至: 中国

Quick Overview for CD200 抗体 (ABIN6240832)

抗原

See all CD200 抗体
CD200

适用

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宿主

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小鼠

克隆类型

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单克隆

标记

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This CD200 antibody is un-conjugated

应用范围

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Flow Cytometry (FACS), Immunohistochemistry (Frozen Sections) (IHC (fro)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

克隆位点

OX-104
  • 原理

    Anti-Hu CD200 Purified

    特异性

    The mouse monoclonal antibody OX-104 recognizes an extracellular epitope of CD200, a type-1 glycoprotein of the immunoglobulin superfamily, which is expressed in neurons, B and T cell subsets, keratinocytes, follicular dendritic cells, and ovarian cells.

    交叉反应 (详细)

    Human

    纯化方法

    Purified by protein-A affinity chromatography.

    纯度

    > 95 % (by SDS-PAGE)

    免疫原

    recombinant human CD200

    亚型

    IgG1 kappa
  • 应用备注

    Flow cytometry: Recommended dilution: 1-4 μg/mL.

    限制

    仅限研究用
  • 浓度

    1 mg/mL

    缓冲液

    Phosphate buffered saline (PBS), pH 7.4, 15 mM sodium azide

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    4 °C

    储存方法

    Store at 2-8°C. Do not freeze.
  • 抗原

    CD200

    别名

    CD200

    背景

    CD200 Molecule,CD200 (also known as OX2 or MRC) is a type-1 membrane glycoprotein, which contains two extracellular immunoglobulin domains, transmembrane domain and cytoplasmic domain. It is expressed by neuronal cells, B and T cell subsets, follicular dendritic cells, keratinocytes, and ovarian cells. The interaction between CD200 and its receptor CD200R results in macrophage activation (IL-6 production), inhibition of mast cell degranulation along with reduced TNF-alpha and IL-13 secretion and overall attenuation of the activation status of lymphocytes. It seems CD200 is also involved in maternal tolerance and its decreased expression in hair follicle correlates with follicular miniaturization.,MRC, MOX, OX-2

    基因ID

    4345

    UniProt

    P41217
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