DcR2 抗体 (AA 1-210) (APC)
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- 抗原 See all DcR2 (TNFRSF10D) 抗体
- DcR2 (TNFRSF10D) (Tumor Necrosis Factor Receptor Superfamily, Member 10d, Decoy with Truncated Death Domain (TNFRSF10D))
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抗原表位
- AA 1-210
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适用
- 人
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宿主
- 小鼠
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克隆类型
- 单克隆
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标记
- This DcR2 antibody is conjugated to APC
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应用范围
- Flow Cytometry (FACS)
- 特异性
- The antibody TRAIL-R4-01 reacts with an extracellular epitope of TRAIL-R4, a 42 kDa transmembrane protein expressed on various blood cells.
- 交叉反应 (详细)
- Human
- 纯化方法
- Purified antibody is conjugated with activated allophycocyanin (APC) under optimum conditions and unconjugated antibody and free fluorochrome are removed by size-exclusion chromatography.
- 免疫原
- TRAIL-R4 (aa 1-210) - hIgGhc fusion protein
- 克隆位点
- TRAIL-R4-01
- 亚型
- IgG1
- Top Product
- Discover our top product TNFRSF10D Primary Antibody
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- 应用备注
- Flow cytometry: Recommended dilution: 1-5 μg/mL.
- 说明
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The purified antibody is conjugated with cross-linked Allophycocyanin (APC) under optimum conditions. The conjugate is purified by size-exclusion chromatography.
- 限制
- 仅限研究用
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- 浓度
- 0.1 mg/mL
- 缓冲液
- Stabilizing phosphate buffered saline (PBS), pH 7.4, 15 mM sodium azide
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 注意事项
- The purified antibody is conjugated with cross-linked Allophycocyanin (APC) under optimum conditions. The conjugate is purified by size-exclusion chromatography.
- 储存条件
- 4 °C
- 储存方法
- Store at 2-8°C. Protect from prolonged exposure to light. Do not freeze.
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- 抗原
- DcR2 (TNFRSF10D) (Tumor Necrosis Factor Receptor Superfamily, Member 10d, Decoy with Truncated Death Domain (TNFRSF10D))
- 别名
- CD264 / TRAIL-R4 (TNFRSF10D 产品)
- 别名
- TNFRSF10D antibody, CD264 antibody, DCR2 antibody, TRAIL-R4 antibody, TRAILR4 antibody, TRUNDD antibody, TNF receptor superfamily member 10d antibody, tumor necrosis factor receptor superfamily member 10D antibody, TNFRSF10D antibody, LOC716901 antibody
- 背景
- TNF receptor superfamily member 10d,TRAIL-R4 (CD264, TR4, DcR2, TRUNDD), expressed mainly on CD8+ and NK cells, belongs to receptors of TRAIL, a TNF-like membrane toxic protein that induces apoptosis in many tumour cells, but not in normal cells. TRAIL-R4, however, contains partially truncated death domain, thus it is unable to induce apoptosis and serves as a negative regulator of apoptotic signaling by impairment death-inducing signaling complex (DISC) processing. TRAIL-R4 interacts with death receptor 5 (DR5) in the native DISC in a TRAIL-dependent manner and prevents its corecruitment with death receptor 4 (DR4).,TNFRSF10D, DcR2, TRUNDD, TRAILR4
- 基因ID
- 8793
- UniProt
- Q9UBN6
- 途径
- Apoptosis
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