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MUTYH 抗体

MUTYH 适用: 人, 小鼠, 大鼠 WB, IHC 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN3022243
发货至: 中国
  • 抗原 See all MUTYH 抗体
    MUTYH (MutY Homolog (E. Coli) (MUTYH))
    适用
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    人, 小鼠, 大鼠
    宿主
    • 51
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    克隆类型
    • 54
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    多克隆
    标记
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    This MUTYH antibody is un-conjugated
    应用范围
    • 28
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    Western Blotting (WB), Immunohistochemistry (IHC)
    纯化方法
    Affinity purification
    免疫原
    Recombinant protein of human MUTYH
    亚型
    IgG
    Top Product
    Discover our top product MUTYH Primary Antibody
  • 应用备注
    Recommended dilutions: WB: 1:500-1:2000, IHC: 1:50-1:200
    限制
    仅限研究用
  • 状态
    Liquid
    缓冲液
    PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3
    储存液
    Sodium azide
    注意事项
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    注意事项
    Avoid freeze / thaw cycles
    储存条件
    -20 °C/-80 °C
  • 抗原
    MUTYH (MutY Homolog (E. Coli) (MUTYH))
    别名
    MUTYH (MUTYH 产品)
    别名
    MUTYH antibody, MGC145569 antibody, CYP2C antibody, MYH antibody, 5730495A01Rik antibody, Mutyha antibody, Mutyhalpha antibody, Mutyhb antibody, Mutyhbeta antibody, Mutyhc antibody, Myh antibody, mutY DNA glycosylase antibody, mutY homolog (E. coli) antibody, A/G-specific adenine DNA glycosylase-like antibody, MUTYH antibody, mutyh antibody, LOC100373318 antibody, Mutyh antibody
    背景
    Base excision repair (BER) proteins catalyze the removal of incorrect or damaged bases, including oxidized bases, from DNA. N-glycosylases specific to a given lesion remove the incorrect base as the first step in BER. MYH is the mammalian ortholog of E. coli MutY, a DNA glycosylase that catalyzes the removal of 8-oxoG:A mismatches. Several MYH isoforms have been detected in human cells localizing to either the nucleus or the mitochondria. MYH interacts with DNA repair proteins and localizes to DNA damage foci after oxidative damage. Research studies have shown that mutations in the corresponding MYH gene are associated with human gastric and colorectal cancers.
    Synonyms: MGC4416, MYH
    基因ID
    4595
    UniProt
    Q9UIF7
    途径
    DNA Damage Repair
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