LGALS13 抗体 (AA 23-134) (CF®568)
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- 抗原 See all LGALS13 抗体
- LGALS13 (Lectin, Galactoside-Binding, Soluble, 13 (LGALS13))
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抗原表位
- AA 23-134
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适用
- 人
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宿主
- 小鼠
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克隆类型
- 单克隆
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标记
- This LGALS13 antibody is conjugated to CF®568
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应用范围
- Immunohistochemistry (IHC), Flow Cytometry (FACS), Immunofluorescence (IF), ELISA, Coating (Coat)
- 原理
- Mouse Monoclonal anti-Galectin-13 / Placental-Protein-13 (PP13/1162), CF568 Conjugate
- 产品特性
- This antibody recognizes a 32 kDa protein, which is identified as homodimer of galectin-13 (also known as PP13). Galectins are a family of soluble ?-galactoside-binding lectins that modulate cell-to-cell adhesion and cell-to-extracellular matrix (ECM) interactions and play a role in tumor progression, pre-mRNA splicing and apoptosis. One such member, galectin-13, is a 139 amino acid protein that contains one galectin domain. Possessing lysophospholipase activity, galectin-13 exists as a disulfide-linked homodimer. Galectin-13 is suggested to have a developmental role in the placenta and may display immunobiological activity in feto-maternal blood-spaces. Screening for galectin-13 in maternal serum during the first trimester of pregnancy may serve as a diagnostic marker to predict preterm pre-eclampsia. Primary antibodies are available purified, or with a selection of fluorescent CF® dyes and other labels. CF® dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.
- 免疫原
- Recombinant human Galectin-13 protein fragment (aa23-134) (exact sequence is proprietary)
- 克隆位点
- PP13-1162
- 亚型
- IgG2b
- Top Product
- Discover our top product LGALS13 Primary Antibody
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- 应用备注
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Immunohistology (formalin) 0.5-1 μg/mL
- Staining of formalin-fixed tissues requires boiling tissue sections in 10 mM Tris, 1 mM EDTA pH 9.0 or 10 mM citrate buffer pH 6.0 for 10-20 min followed by cooling at RT for 20 min
- Immunofluorescence 0.5-1 μg/mL
- Flow Cytometry 0.5-1 μg/million cells/0.1 mL
- ELISA For coating, order Ab without BSA
- Optimal dilution for a specific application should be determined by user
- 说明
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K-562 cells. Placenta or Spleen.
- 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- 100 μg/mL
- 缓冲液
- PBS/0.1 % BSA/0.05 % azide
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 注意事项
- Protect from light
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- 抗原
- LGALS13 (Lectin, Galactoside-Binding, Soluble, 13 (LGALS13))
- 别名
- Galectin-13 / Placental-Protein-13 (LGALS13 产品)
- 别名
- GAL13 antibody, PLAC8 antibody, PP13 antibody, Gal-11 antibody, Gal-13 antibody, Gal11 antibody, gal-13 antibody, galectin 13 antibody, avian beta-defensin 13 antibody, LGALS13 antibody, AvBD13 antibody
- 背景
- Gal-13, GAL13, Galactoside-binding soluble lectin 13, Galectin-13, Galectin13, Lectin galactoside binding soluble 13, LGALS13, PLAC8, Placental protein 13 (PP13), Placental tissue protein 13
- 分子量
- 16 kDa (monomer), 32 kDa (homodimer)
- 基因ID
- 29124, 23671
- UniProt
- Q9UHV8
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