Nkx2-2 抗体 (CF®594)
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- 抗原 See all Nkx2-2 抗体
- Nkx2-2 (NK2 Homeobox 2 (Nkx2-2))
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适用
- 人, 小鼠, 大鼠, 小鸡
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宿主
- 小鼠
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克隆类型
- 单克隆
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标记
- This Nkx2-2 antibody is conjugated to CF®594
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应用范围
- Immunofluorescence (IF), Flow Cytometry (FACS), Immunohistochemistry (Formalin-fixed Sections) (IHC (f))
- 原理
- Mouse Monoclonal anti-NKX2.2 (NX2/294), CF594 Conjugate
- 产品特性
- Expression of NKX2.2 has been found in neuroendocrine tumors of the gut, making it a potential marker for the study of gastrointestinal neuroendocrine tumors. More recently, NKX2.2 protein was identified as a target of EWS-FLI-1, the fusion protein specific to Ewing sarcoma, and was shown to be differentially upregulated in Ewing sarcoma on the basis of array-based gene expression analysis. It acts as a valuable marker for Ewing sarcoma, with a sensitivity of 93 % and a specificity of 89 %, and aids in the differential diagnosis of small round cell tumors. Primary antibodies are available purified, or with a selection of fluorescent CF® dyes and other labels. CF® dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.
- 免疫原
- Human full-length recombinant NKX2.2 protein
- 克隆位点
- NX2-294
- 亚型
- IgG2b kappa
- Top Product
- Discover our top product Nkx2-2 Primary Antibody
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- 应用备注
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Immunohistology formalin-fixed 0.5-1 μg/mL
- Staining of formalin-fixed tissues requires boiling tissue sections in 10 mM citrate buffer, pH 6.0, for 10-20 min followed by cooling at RT for 20 minutes
- Flow Cytometry 0.5-1 μg/million cells/0.1 mL
- Immunofluorescence 1-2 μg/mL
- Optimal dilution for a specific application should be determined by user
- 说明
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Pancreas or Ewing s sarcoma
- 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- 100 μg/mL
- 缓冲液
- PBS/0.1 % BSA/0.05 % azide
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 注意事项
- Protect from light
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- 抗原
- Nkx2-2 (NK2 Homeobox 2 (Nkx2-2))
- 别名
- NKX2.2 (Nkx2-2 产品)
- 别名
- XeNK-2 antibody, Xnkx2.2 antibody, nkx2-2-A antibody, nkx2.2 antibody, NKX-2.2 antibody, NKX2.2 antibody, NKX2B antibody, Nkx-2.2 antibody, Nkx2.2 antibody, tinman antibody, id:ibd5090 antibody, nk2.2 antibody, nkx2-2 antibody, wu:fc83b01 antibody, zgc:136536 antibody, NK2 homeobox 2 S homeolog antibody, NK2 homeobox 2 antibody, NK2 homeobox 2a antibody, nkx2-2.S antibody, NKX2-2 antibody, Nkx2-2 antibody, nkx2.2a antibody
- 背景
- Homeobox protein NK-2 homolog B, NK2 transcription factor like protein B, NK2 transcription factor related locus 2, NKX22, Nkx2b, tinman
- 分子量
- 40-50 kDa
- 基因ID
- 4821, 516922
- UniProt
- O95096
- 途径
- Dopaminergic Neurogenesis
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