CD37 抗体
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- 抗原 See all CD37 (TSPAN26) 抗体
- CD37 (TSPAN26) (Tetraspanin 26 (TSPAN26))
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适用
- 人
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宿主
- 小鼠
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克隆类型
- 单克隆
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标记
- This CD37 antibody is un-conjugated
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应用范围
- Flow Cytometry (FACS), Immunofluorescence (IF)
- 原理
- Mouse Monoclonal anti-CD37 (IPO-24), Purified, with BSA
- 产品特性
- This antibody recognizes a protein of 33-55 kDa, identified as CD37 (Workshop V, Code CD37.7). CD37 is strongly expressed on normal and neoplastic mature (sIg ) B-lymphocytes. In B-cell ontogeny, CD37 appears after the pre-B-cell stage, is maintained during peripheral B-cell development and is lost upon terminal differentiation into plasma cells.1 CD37 is also present, at low densities, on resting and activated T cells, neutrophils, monocytes, and some myelomonocytic leukemia cells. It is absent from platelets, erythrocytes. CD37 is a member of a family of tetraspan transmembrane proteins, including CD9, CD53, CD63, CD81, and CD82. It associates other tetraspan transmembrane proteins and MHC class II molecules to form a large complex at the surface of B cells and play a role in signal transduction. CD37 is a valuable and stable marker for peripheral mature B-cells and corresponding malignancies like B-cell chronic lymphocytic leukemia (B-CLL), hairy cell leukemia (HCL), and all types of B-cell non-Hodgkin'' lymphoma (B-NHL). Primary antibodies are available purified, or with a selection of fluorescent CF® dyes and other labels. CF® dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.
- 纯化方法
- Purified
- 免疫原
- Spleen cells of a patient with hairy cell leukemia
- 克隆位点
- IPO-24
- 亚型
- IgG2b kappa
- Top Product
- Discover our top product TSPAN26 Primary Antibody
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- 应用备注
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Immunofluorescence 0.5-1 μg/mL
- Flow Cytometry 0.5-1 μg/million cells/0.1 mL
- Optimal dilution for a specific application should be determined by user
- 说明
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Daudi, Raji, Namalva, Ramos cells and human lymphocytes. Human tonsil and lymph node.
- 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- 200 μg/mL
- 缓冲液
- PBS/0.05 % BSA/0.05 % azide
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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- 抗原
- CD37 (TSPAN26) (Tetraspanin 26 (TSPAN26))
- 别名
- CD37 (TSPAN26 产品)
- 别名
- Tspan26 antibody, GP52-40 antibody, TSPAN26 antibody, CD37 antigen antibody, CD37 molecule antibody, Cd37 antibody, CD37 antibody
- 背景
- Cell differentiation antigen 37, GP52 40, Tetraspanin-26, Tspan-26, TSPAN26
- 分子量
- 33-55 kDa
- 基因ID
- 951, 166556
- UniProt
- P11049
- 途径
- Positive Regulation of Immune Effector Process, Production of Molecular Mediator of Immune Response
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