Plakophilin 1 抗体 (N-Term) (CF®647)
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- 抗原 See all Plakophilin 1 (PKP1) 抗体
- Plakophilin 1 (PKP1)
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抗原表位
- N-Term
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适用
- 人, 小鼠
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宿主
- 小鼠
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克隆类型
- 单克隆
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标记
- This Plakophilin 1 antibody is conjugated to CF®647
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应用范围
- Western Blotting (WB), Immunofluorescence (IF), Flow Cytometry (FACS)
- 原理
- Mouse Monoclonal anti-Plakophilin-1 (10B2), CF647 Conjugate
- 产品特性
- This antibody recognizes a protein of 75 kDa, identified as Plakophilin-1. Its epitope maps between aa 1-27 human Plakophilin-1. Plakophilins 1, 2, 3 and 4 (PKP1-4) influence development and participate in linking cadherins to cytoskeletal intermediate filaments. Plakophilins 1-4 contain arm-repeat (armadillo) domains and localize to nuclei and cell desmosomes (cell-cell junctions found in suprabasal layers of stratifying epithelia that undergo mechanical stress). Plakophilin 2 is important for desmosome assembly and is an essential morphogenic factor and architectural component of the heart. Primary antibodies are available purified, or with a selection of fluorescent CF® dyes and other labels. CF® dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.
- 免疫原
- N-terminus of human Plakophilin-1 protein (exact sequence is proprietary)
- 克隆位点
- 10B2
- 亚型
- IgG1
- Top Product
- Discover our top product PKP1 Primary Antibody
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- 应用备注
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Flow Cytometry 0.5-1 μg/million cells/0.1 mL
- Immunofluorescence 1-2 μg/mL
- Western blotting 0.5-1 μg/mL
- Optimal dilution for a specific application should be determined by user
- 说明
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HaCat Cells.
- 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- 100 μg/mL
- 缓冲液
- PBS/0.1 % BSA/0.05 % azide
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 注意事项
- Protect from light
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- 抗原
- Plakophilin 1 (PKP1)
- 别名
- Plakophilin-1 (PKP1 产品)
- 别名
- PKP1 antibody, fb30d08 antibody, wu:fb30d08 antibody, AI528551 antibody, B6P antibody, plakophilin 1 antibody, plakophilin 1b antibody, PKP1 antibody, pkp1b antibody, Pkp1 antibody
- 背景
- B6P, B, 6 protein, PKP1, Plakophilin-1 (ectodermal dysplasia/skin fragility syndrome)
- 分子量
- 75 kDa
- 基因ID
- 5317, 497350
- UniProt
- Q13835
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