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CD44v6 抗体 (CF®405S)

适用: 人 FACS, IF, IHC 宿主: 小鼠 Monoclonal CD44v6-1246 CF®405S
产品编号 ABIN6165423
发货至: 中国
  • 抗原
    CD44v6
    适用
    • 20
    • 2
    宿主
    • 19
    • 2
    • 1
    小鼠
    克隆类型
    • 21
    • 1
    单克隆
    标记
    • 14
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    CF®405S
    应用范围
    • 16
    • 11
    • 11
    • 8
    • 7
    • 4
    • 3
    • 1
    • 1
    Flow Cytometry (FACS), Immunofluorescence (IF), Immunohistochemistry (IHC)
    原理
    Mouse Monoclonal anti-CD44v6 (CD44v6/1246), CF405S Conjugate
    产品特性
    This antibody recognizes an epitope encoded by exon v6 on the variant portion of human CD44. The CD44 Molecule belongs to a family of cellular adhesion molecules found on a wide range of normal and malignant cells in epithelial, mesothelial and hemopoiesis tissues. CD44 is a single gene with 20 exons, of which 10 are normally expressed to encode the basic CD44 (H-CAM) molecule. The additional 10 exons (v1 to v10) are only expressed by alternative splicing of the nuclear RNA. The expression of specific cell adhesion molecule CD44 splice variants has been reported to be associated with metastasis in certain human malignancies. Primary antibodies are available purified, or with a selection of fluorescent CF® dyes and other labels. CF® dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.
    免疫原
    Recombinant fragment corresponding to the v6 domain of human CD44 (exact sequence is proprietary)
    克隆位点
    CD44v6-1246
    亚型
    IgG2a kappa
  • 应用备注
    Immunohistology (formalin) 0.5-1 μg/mL
    • Staining of formalin-fixed tissues requires boiling tissue sections in 10 mM citrate buffer,  pH 6.0, for 10-20 min followed by cooling at RT for 20 min
    • Immunofluorescence 0.5-1 μg/mL
    • Flow Cytometry 0.5-1 μg/million cells/0.1 mL
    • Optimal dilution for a specific application should be determined by user
    说明

    Cervix or Tongue Squamous Cell Carcinoma

    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    100 μg/mL
    缓冲液
    PBS/0.1 % BSA/0.05 % azide
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    注意事项
    Protect from light
  • 抗原
    CD44v6
    分子量
    80-95 kDa
    基因ID
    960, 502328
    UniProt
    P16070
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