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JUP 抗体 (Biotin)

JUP 适用: 人, 小鼠, 大鼠, 小鸡, Cow, 犬, Cat WB, IF, FACS 宿主: 小鼠 Monoclonal 15F11 Biotin
产品编号 ABIN6164920
发货至: 中国
  • 抗原 See all JUP 抗体
    JUP (Junction Plakoglobin (JUP))
    适用
    • 149
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    人, 小鼠, 大鼠, 小鸡, Cow, 犬, Cat
    宿主
    • 93
    • 56
    • 2
    • 1
    小鼠
    克隆类型
    • 85
    • 67
    单克隆
    标记
    • 69
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    This JUP antibody is conjugated to Biotin
    应用范围
    • 112
    • 54
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    • 10
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    Western Blotting (WB), Immunofluorescence (IF), Flow Cytometry (FACS)
    原理
    Mouse Monoclonal anti-Catenin, gamma (15F11), Biotin Conjugate
    产品特性
    This antibody recognizes a protein of 80-87 kDa, identified as gamma-catenin. The catenins (?, ?, ? and ?) are ubiquitously expressed, cytoplasmic proteins that associate with E-cadherin at cellular junctions. Catenin/cadherin complexes play an important role in mediating cellular adhesion. ? T-catenin, also referred to as VR22, is a 895-amino acid protein that is most abundantly expressed in cardio-myocytes and in the peritubular myoid cells of the testis. ? T-catenin binds to ? E-catenin as well as to ?-catenin, and it functions to inhibit Wnt signaling. CTNNA3, the gene that encodes for ?-T-catenin, is located on chromosome 10, and mutations in this gene show a strong correlation to late-onset Alzheimer s disease (LOAD) as well as to dilated cardiomyopathy. Primary antibodies are available purified, or with a selection of fluorescent CF® dyes and other labels. CF® dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.
    免疫原
    full length chicken Catenin gamma protein|Recombinant
    克隆位点
    15F11
    亚型
    IgG1 kappa
    Top Product
    Discover our top product JUP Primary Antibody
  • 应用备注
    Flow Cytometry 0.5-1 μg/million cells/0.1 mL
    • Immunofluorescence 1-2 μg/mL
    • Western blotting 0.5-1 μg/mL
    • Optimal dilution for a specific application should be determined by user
    说明

    A431, T47D or MCF-7 cells. Skin

    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    100 μg/mL
    缓冲液
    PBS/0.1 % BSA/0.05 % azide
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
  • 抗原
    JUP (Junction Plakoglobin (JUP))
    别名
    Catenin, gamma (JUP 产品)
    别名
    ARVD12 antibody, CTNNG antibody, DP3 antibody, DPIII antibody, PDGB antibody, PKGB antibody, arvd12 antibody, ctnng antibody, dp3 antibody, dpiii antibody, pdgb antibody, pkgb antibody, plak antibody, D930025P04Rik antibody, PG antibody, cb80 antibody, danPG antibody, fb11b06 antibody, jup antibody, wu:fb11b06 antibody, junction plakoglobin antibody, junction plakoglobin L homeolog antibody, Junction plakoglobin antibody, junction plakoglobin a antibody, junction plakoglobin S homeolog antibody, JUP antibody, Jup antibody, jup antibody, jup.L antibody, Tsp_06656 antibody, plak antibody, jupa antibody, jup.S antibody
    背景
    ARVD12, Catenin (cadherin-associated protein), gamma 80  kDa, Catenin gamma, CTNNG, Desmoplakin III, Desmoplakin-3, DP3, DPIII, Junction Plakoglobin, PDGB, PKGB
    分子量
    80-87 kDa
    基因ID
    3728, 514174
    UniProt
    P14923
    途径
    Cell-Cell Junction Organization, Maintenance of Protein Location
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