Melanoma Marker 抗体
适用: 人
IHC, IF
宿主: 小鼠
Monoclonal
KBA-62
unconjugated
2 images
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- 抗原 See all Melanoma Marker products
- Melanoma Marker
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适用
- 人
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宿主
- 小鼠
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克隆类型
- 单克隆
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标记
- This Melanoma Marker antibody is un-conjugated
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应用范围
- Immunohistochemistry (IHC), Immunofluorescence (IF)
- 原理
- Mouse Monoclonal anti-Melanoma Marker (KBA.62), Purified, BSA-free
- 产品特性
- KBA.62 is a novel anti-melanoma antibody. It reacts positively against melanocytic tumors but not other tumors, thus demonstrating specificity and sensitivity. Moreover, it reacts positively against junctional nevus cells but not intradermal nevi, and against fetal melanocytes but not normal adult melanocytes. KBA.62 antibody is useful in identifying malignant melanomas. Metastatic amelanotic melanoma can often be confused with a variety of poorly differentiated carcinomas, large cell lymphomas, sarcomas, spindle cell carcinomas and various types of mesenchymal neoplasms. A keratin-negative, vimentin-rich neoplasm that immuno-reacts with antibody to S-100 protein and with KBA.62 antibody is, with rare exception, a melanoma. Anti-KBA.62 is a useful additional marker for melanoma, specifically in desmoplastic/spindle cell cases and in the context of micro-metastasis in sentinel lymph node. Primary antibodies are available purified, or with a selection of fluorescent CF® dyes and other labels. CF® dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.
- 纯化方法
- Purified
- 免疫原
- Human KAL cells derived from lymph node metastasis of malignant melanoma
- 克隆位点
- KBA-62
- 亚型
- IgG1 kappa
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anti-Melanoma Marker antibody
适用: 人 IHC (p) 宿主: 小鼠 Monoclonal HMB45 unconjugated
anti-Melanoma Marker antibody适用: 人, 犬, 小鼠 IHC, IF 宿主: 小鼠 Monoclonal PNL2 unconjugated
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- 应用备注
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Immunohistology (formalin)
- Staining of formalin-fixed tissues requires boiling tissue sections in 10 mM citrate buffer, pH 6.0, for 10-20 min followed by cooling at RT for 20 minutes
- Immunofluorescence 0.5-1 μg/mL
- Optimal dilution for a specific application should be determined by user
- 说明
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SK-MEL-13 and SK-MEL-19 Melanoma cell lines, Melanomas
- 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- 1 mg/mL
- 缓冲液
- PBS (no BSA, no azide)
- 储存液
- Azide free
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- 抗原
- Melanoma Marker
- Abstract
- Melanoma Marker 产品
- 背景
- Human Melanoma Associated Antigen, KBA.62
- 分子量
- Multiple (140, 135 and 128 kDa and two weak bands of 88 and 73 kDa)
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