Coagulation Factor X 抗体
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- 抗原 See all Coagulation Factor X (F10) 抗体
- Coagulation Factor X (F10)
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适用
- 人
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宿主
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绵羊
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克隆类型
- 多克隆
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标记
- This Coagulation Factor X antibody is un-conjugated
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应用范围
- Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Enzyme Immunoassay (EIA), Immunoelectrophoresis (IEP), Immunodiffusion (ID)
- 特异性
- This antibody detects Coagulation factor X (F10). Only one arc was seen with normal plasma. No arc was seen with Factor X deficient plasma.
- 交叉反应 (详细)
- Species reactivity (tested):Human.
- 纯化方法
- Immunoaffinity Chromatography
- 免疫原
- Human Factor X purified from plasma, activated and active site blocked
- 亚型
- IgG
- Top Product
- Discover our top product F10 Primary Antibody
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- 应用备注
- Optimal working dilution should be determined by the investigator.
- 限制
- 仅限研究用
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- 浓度
- 1.0 mg/mL
- 缓冲液
- 10 mM HEPES, pH 7.4, 0.15 M Sodium Chloride, 50 % Glycerol
- 注意事项
- Avoid repeated freezing and thawing.
- 储存条件
- 4 °C/-20 °C
- 储存方法
- Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
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- 抗原
- Coagulation Factor X (F10)
- Abstract
- F10 产品
- 别名
- FX antibody, FXA antibody, Cf10 antibody, fX antibody, fi12c10 antibody, wu:fi12c10 antibody, F10 antibody, f10 antibody, coagulation factor X antibody, Coagulation factor X antibody, coagulation factor 10 L homeolog antibody, F10 antibody, f10 antibody, CpipJ_CPIJ012712 antibody, CpipJ_CPIJ014863 antibody, CpipJ_CPIJ016937 antibody, CpipJ_CPIJ017791 antibody, fa10 antibody, f10.L antibody
- 背景
- F10 is the vitamin K-dependent coagulation factor X of the blood coagulation cascade. This factor undergoes multiple processing steps before its preproprotein is converted to a mature two-chain form by the excision of the tripeptide RKR. Two chains of the factor are held together by 1 or more disulfide bonds, the light chain contains 2 EGF-like domains, while the heavy chain contains the catalytic domain which is structurally homologous to those of the other hemostatic serine proteases. The mature factor is activated by the cleavage of the activation peptide by factor IXa (in the intrisic pathway), or by factor VIIa (in the extrinsic pathway). The activated factor then converts prothrombin to thrombin in the presence of factor Va, Ca+2, and phospholipid during blood clotting.Synonyms: Stuart factor, Stuart-Prower factor
- 基因ID
- 2159
- NCBI登录号
- NP_000495
- UniProt
- P00742
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