FAT Atypical Cadherin 2 (FAT2) 抗体 (CF®488A)
-
- 抗原 See all FAT Atypical Cadherin 2 (FAT2) 抗体
- FAT Atypical Cadherin 2 (FAT2)
-
适用
- 人
-
宿主
- 小鼠
-
克隆类型
- 单克隆
-
标记
- CF®488A
-
应用范围
- Immunofluorescence (IF), Flow Cytometry (FACS), Immunohistochemistry (IHC)
- 原理
- Mouse Monoclonal anti-Protocadherin-FAT2 (8C5), CF488A Conjugate
- 产品特性
- This antibody recognizes a protein of 480 kDa, which is identified as FAT2. The cadherins represent a family of Ca2 -dependent adhesion molecules that function to mediate cell-to-cell binding that is critical for the maintenance of structure and morphogenesis. Cadherins each contain a large extracellular domain at the N-terminus, which is characterized by a series of five homologous repeats, the most distal of which is thought to be responsible for binding specificity. The relatively short C-terminal intracellular domain interacts with a variety of cytoplasmic proteins, including ?-catenin, to regulate cadherin function. The cadherin superfamily includes cadherins, protocadherins, desmogleins and desmocollins. FAT2 (FAT tumor suppressor homolog 2) is a single-pass type I membrane protein that belongs to the protocadherin subfamily of cadherins. FAT2 contains one Laminin G-like domain, two EGF-like domains and 32 cadherin domains and is believed to function as a cell adhesion molecule, controlling cell proliferation and playing an important role in cerebellum development. Primary antibodies are available purified, or with a selection of fluorescent CF® dyes and other labels. CF® dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.
- 免疫原
- Purified recombinant human FAT2 fusion protein
- 克隆位点
- 8C5
- 亚型
- IgG1 kappa
- Top Product
- Discover our top product FAT2 Primary Antibody
-
anti-FAT Atypical Cadherin 2 (FAT2) (AA 123-314) antibody
FAT2 适用: 人 IF, IHC, ELISA 宿主: 兔 Polyclonal unconjugated
anti-FAT Atypical Cadherin 2 (FAT2) antibodyFAT2 适用: 人 IF, FACS, IHC, StM 宿主: 小鼠 Monoclonal 8C5 unconjugated
-
- 应用备注
-
Immunohistology (formalin) 0.5-1 μg/mL
- Staining of formalin-fixed tissues requires boiling tissue sections in 10 mM citrate buffer, pH 6.0, for 10-20 min followed by cooling at RT for 20 min
- Flow Cytometry 0.5-1 μg/million cells/0.1 mL
- Immunofluorescence 1-2 μg/mL
- Optimal dilution for a specific application should be determined by user
- 说明
-
Esophagus, Cervix, Uterus, Tonsil or Cerebellum.
- 限制
- 仅限研究用
-
- 状态
- Liquid
- 浓度
- 100 μg/mL
- 缓冲液
- PBS/0.1 % BSA/0.05 % azide
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 注意事项
- Protect from light
-
- 抗原
- FAT Atypical Cadherin 2 (FAT2)
- 别名
- Protocadherin-FAT2 (FAT2 产品)
- 别名
- EMI2 antibody, Fath2 antibody, Gm523 antibody, mKIAA0811 antibody, CDHF8 antibody, CDHR9 antibody, HFAT2 antibody, MEGF1 antibody, FAT atypical cadherin 2 antibody, Fat2 antibody, FAT2 antibody
- 分子量
- 480 kDa
- 基因ID
- 2196, 591255
- UniProt
- Q9NYQ8
-
