HLA-DP beta 抗体
HLA-DP beta
适用: 人
FACS, IF, IHC (f)
宿主: 小鼠
Monoclonal
Bra-14
unconjugated
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- 抗原 See all HLA-DP beta products
- HLA-DP beta (MHC Class II HLA-DP beta (HLA-DP beta))
- 适用
- 人
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宿主
- 小鼠
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克隆类型
- 单克隆
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标记
- This HLA-DP beta antibody is un-conjugated
- 应用范围
- Flow Cytometry (FACS), Immunofluorescence (IF), Immunohistochemistry (Formalin-fixed Sections) (IHC (f))
- 原理
- Mouse Monoclonal anti-MHC-II (HLA-DP beta chain) (Bra-14), Purified, with BSA
- 产品特性
- This antibody recognizes a common epitope of human major histocompatibility (MHC) class II antigens, HLA-DR and DP. Human MHC class II antigens are transmembrane glycoproteins composed of an chain (36 kDa) and a chain (27 kDa). They are expressed primarily on antigen presenting cells such as B lymphocytes, monocytes, macrophages, and thymic epithelial cells and are also present on activated T lymphocytes. Human MHC class II genes are located in the HLA-D region that encodes at least six and ten chain genes. Three loci, DR, DQ and DP, encode the major expressed products of the human class II region. The human MHC class II molecules bind intracellularly processed peptides and present them to T-helper cells. They, therefore, have a critical role in the initiation of the immune response. It has been shown that some autoimmune diseases are associated with certain class II alleles. Primary antibodies are available purified, or with a selection of fluorescent CF® dyes and other labels. CF® dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.
- 纯化方法
- Purified
- 免疫原
- Human REH cells
- 克隆位点
- Bra-14
- 亚型
- IgG3 kappa
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anti-MHC Class II HLA-DP beta (HLA-DP beta) antibody
HLA-DP beta 适用: 人 FACS, IF, IHC (f) 宿主: 小鼠 Monoclonal Bra-14 unconjugated
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- 应用备注
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Immunohistology formalin-fixed 0.5-1 μg/mL
- Staining of formalin-fixed tissues requires boiling tissue sections in 10 mM citrate buffer, pH 6.0, for 10-20 min followed by cooling at RT for 20 minutes
- Immunofluorescence 0.5-1 μg/mL
- Flow Cytometry 0.5-1 μg/million cells/0.1 mL
- Optimal dilution for a specific application should be determined by user
- 说明
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Raji cells. Tonsil or lymph node
- 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- 200 μg/mL
- 缓冲液
- PBS/0.05 % BSA/0.05 % azide
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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- 抗原
- HLA-DP beta (MHC Class II HLA-DP beta (HLA-DP beta))
- 别名
- MHC-II (HLA-DP) (beta chain) (HLA-DP beta 产品)
- 分子量
- 36 kDa (? chain) and 27 kDa (? chain)
- 基因ID
- 3115, 3122
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