This gene encodes a member of the ZIC family of C2H2-type zinc finger proteins. This nuclear protein probably functions as a transcription factor in early stages of left-right body axis formation. Mutations in this gene cause X-linked visceral heterotaxy, which includes congenital heart disease and left-right axis defects in organs.,ZIC3,HTX,HTX1,VACTERLX,ZNF203,Epigenetics & Nuclear Signaling,Transcription Factors,Cell Biology & Developmental Biology,Stem Cells,Embryonic Stem Cells,ZIC3