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XPC 抗体 (AA 700-940)

XPC 适用: 人 WB, IHC, IP 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN6150295
发货至: 中国
  • 抗原 See all XPC 抗体
    XPC (Xeroderma Pigmentosum, Complementation Group C (XPC))
    抗原表位
    • 14
    • 8
    • 5
    • 3
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    AA 700-940
    适用
    • 47
    • 3
    • 3
    • 1
    宿主
    • 44
    • 7
    克隆类型
    • 45
    • 6
    多克隆
    标记
    • 28
    • 5
    • 4
    • 4
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This XPC antibody is un-conjugated
    应用范围
    • 36
    • 27
    • 10
    • 6
    • 6
    • 6
    • 3
    • 3
    • 2
    • 1
    • 1
    • 1
    Western Blotting (WB), Immunohistochemistry (IHC), Immunoprecipitation (IP)
    序列
    GEVPYKMVKG FSNRARKARL AEPQLREEND LGLFGYWQTE EYQPPVAVDG KVPRNEFGNV YLFLPSMMPI GCVQLNLPNL HRVARKLDID CVQAITGFDF HGGYSHPVTD GYIVCEEFKD VLLTAWENEQ AVIERKEKEK KEKRALGNWK LLAKGLLIRE RLKRRYGPKS EAAAPHTDAG GGLSSDEEEG TSSQAEAARI LAASWPQNRE DEEKQKLKGG PKKTKREKKA AASHLFPFEQ L
    交叉反应
    产品特性
    Polyclonal Antibodies
    免疫原
    Recombinant fusion protein containing a sequence corresponding to amino acids 700-940 of human XPC (NP_004619.3).
    亚型
    IgG
  • 应用备注
    WB,1:500 - 1:2000,IHC,1:50 - 1:100,IP,1:50 - 1:100
    说明

    HIGH QUALITY

    限制
    仅限研究用
  • 状态
    Liquid
    缓冲液
    PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    -20 °C
    储存方法
    Store at -20°C. Avoid freeze / thaw cycles.
  • Gu, Chang, Dai, Song, Zhao, Lei: "Identification of four novel XPC mutations in two xeroderma pigmentosum complementation group C patients and functional study of XPC Q320X mutant." in: Gene, Vol. 628, pp. 162-169, (2017) (PubMed).

  • 抗原
    XPC (Xeroderma Pigmentosum, Complementation Group C (XPC))
    别名
    XPC (XPC 产品)
    别名
    RAD4 antibody, XP3 antibody, XPCC antibody, XPC complex subunit, DNA damage recognition and repair factor antibody, xeroderma pigmentosum, complementation group C antibody, XPC antibody, Xpc antibody
    背景
    This gene encodes a component of the nucleotide excision repair (NER) pathway. There are multiple components involved in the NER pathway, including Xeroderma pigmentosum (XP) A-G and V, Cockayne syndrome (CS) A and B, and trichothiodystrophy (TTD) group A, etc. This component, XPC, plays an important role in the early steps of global genome NER, especially in damage recognition, open complex formation, and repair protein complex formation. Mutations in this gene or some other NER components result in Xeroderma pigmentosum, a rare autosomal recessive disorder characterized by increased sensitivity to sunlight with the development of carcinomas at an early age. Alternatively spliced transcript variants have been found for this gene.,XPC,RAD4,XP3,XPCC,p125,Epigenetics & Nuclear Signaling,DNA Damage & Repair,XPC
    分子量
    15 kDa/101 kDa/105 kDa
    基因ID
    7508
    UniProt
    Q01831
    途径
    p53 Pathway, DNA Damage Repair
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