ULK1 抗体 (AA 400-499)
(1 reference)-
- 抗原 See all ULK1 抗体
- ULK1 (Unc-51 Like Kinase 1 (ULK1))
-
抗原表位
- AA 400-499
-
适用
- 人
-
宿主
- 兔
-
克隆类型
- 多克隆
-
标记
- This ULK1 antibody is un-conjugated
-
应用范围
- Western Blotting (WB), Immunofluorescence (IF)
- 序列
- RTPSPSPPCS SSPSPSGRAG PFSSSRCGAS VPIPVPTQVQ NYQRIERNLQ SPTQFQTPRS SAIRRSGSTS PLGFARASPS PPAHAEHGGV LARKMSLGGG
- 交叉反应
- 人, 小鼠, 大鼠
- 产品特性
- Polyclonal Antibodies
- 纯化方法
- Affinity purification
- 免疫原
- Recombinant fusion protein containing a sequence corresponding to amino acids 400-499 of human ULK1 (NP_003556.1).
- 亚型
- IgG
- Top Product
- Discover our top product ULK1 Primary Antibody
-
anti-Unc-51 Like Kinase 1 (ULK1) (AA 951-1050) antibody
ULK1 适用: 人, 小鼠, 大鼠 ELISA, WB, FACS, IF (cc), IF (p), IHC (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-Unc-51 Like Kinase 1 (ULK1) (AA 602-715) antibodyULK1 适用: 人 ELISA, WB 宿主: 小鼠 Monoclonal 2H8 unconjugated
anti-Unc-51 Like Kinase 1 (ULK1) antibodyULK1 适用: 人, 小鼠 ELISA, WB, IHC, FACS 宿主: 兔 Polyclonal unconjugated
anti-Unc-51 Like Kinase 1 (ULK1) (pSer556) antibodyULK1 适用: 人, 小鼠, 大鼠 ELISA, WB, FACS, IF (cc), IF (p), IHC (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-Unc-51 Like Kinase 1 (ULK1) (AA 567-577) antibodyULK1 适用: 人 WB, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-Unc-51 Like Kinase 1 (ULK1) (AA 567-577) antibody (APC)ULK1 适用: 人 WB, IF, ICC 宿主: 兔 Polyclonal APC
anti-Unc-51 Like Kinase 1 (ULK1) (AA 567-577) antibody (Atto 488)ULK1 适用: 人 WB, IF, ICC 宿主: 兔 Polyclonal Atto 488
anti-Unc-51 Like Kinase 1 (ULK1) (AA 567-577) antibody (Atto 594)ULK1 适用: 人 WB, IF, ICC 宿主: 兔 Polyclonal Atto 594
anti-Unc-51 Like Kinase 1 (ULK1) (AA 567-577) antibody (Atto 390)ULK1 适用: 人 WB, IF, ICC 宿主: 兔 Polyclonal Atto 390
anti-Unc-51 Like Kinase 1 (ULK1) (AA 567-577) antibody (HRP)ULK1 适用: 人 WB, IF, ICC 宿主: 兔 Polyclonal HRP
-
- 应用备注
- WB,1:500 - 1:1000,IF,1:10 - 1:100
- 限制
- 仅限研究用
-
- 状态
- Liquid
- 缓冲液
- PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- -20 °C
- 储存方法
- Store at -20°C. Avoid freeze / thaw cycles.
-
-
: "Activation of the SphK1/ERK/p-ERK pathway promotes autophagy in colon cancer cells." in: Oncology letters, Vol. 15, Issue 6, pp. 9719-9724, (2018) (PubMed).
-
: "Activation of the SphK1/ERK/p-ERK pathway promotes autophagy in colon cancer cells." in: Oncology letters, Vol. 15, Issue 6, pp. 9719-9724, (2018) (PubMed).
-
- 抗原
- ULK1 (Unc-51 Like Kinase 1 (ULK1))
- 别名
- ULk1 (ULK1 产品)
- 别名
- ATG1 antibody, ATG1A antibody, UNC51 antibody, Unc51.1 antibody, hATG1 antibody, si:dkey-11o18.7 antibody, ulk1 antibody, ULK1 antibody, AU041434 antibody, mKIAA0722 antibody, zgc:195008 antibody, unc-51 like autophagy activating kinase 1 antibody, unc-51 like kinase 1 antibody, unc-51 like autophagy activating kinase 1a antibody, ULK1 antibody, Ulk1 antibody, ulk1b antibody, ulk1a antibody
- 背景
- Serine/threonine-protein kinase involved in autophagy in response to starvation. Acts upstream of phosphatidylinositol 3-kinase PIK3C3 to regulate the formation of autophagophores, the precursors of autophagosomes. Part of regulatory feedback loops in autophagy: acts both as a downstream effector and negative regulator of mammalian target of rapamycin complex 1 (mTORC1 via interaction with RPTOR. Activated via phosphorylation by AMPK and also acts as a regulator of AMPK by mediating phosphorylation of AMPK subunits PRKAA1, PRKAB2 and PRKAG1, leading to negatively regulate AMPK activity. May phosphorylate ATG13/KIAA0652 and RPTOR, however such data need additional evidences. Plays a role early in neuronal differentiation and is required for granule cell axon formation. May also phosphorylate SESN2 and SQSTM1 to regulate autophagy. Phosphorylates FLCN, promoting autophagy. Phosphorylates AMBRA1 in response to autophagy induction, releasing AMBRA1 from the cytoskeletal docking site to induce autophagosome nucleation.,ULK1,ATG1,ATG1A,UNC51,Unc51.1,hATG1,ULk1,Signal Transduction,Kinase,Serine/threonine kinases,PI3K-Akt Signaling Pathway,Cell Biology & Developmental Biology,Autophagy,Endocrine & Metabolism,Mitochondrial metabolism,Mitophagy fission and fusion,Neuroscience,Cardiovascular,Heart,Regulator of mTOR complex function,Regulators,ULk1
- 分子量
- 112 kDa
- 基因ID
- 8408
- UniProt
- O75385
- 途径
- Regulation of Cell Size, Autophagy
-
