TXNRD2 抗体 (AA 100-310)
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- 抗原 See all TXNRD2 抗体
- TXNRD2 (Thioredoxin Reductase 2 (TXNRD2))
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抗原表位
- AA 100-310
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适用
- 人
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This TXNRD2 antibody is un-conjugated
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应用范围
- Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF)
- 序列
- AALLGGLIQD APNYGWEVAQ PVPHDWRKMA EAVQNHVKSL NWGHRVQLQD RKVKYFNIKA SFVDEHTVCG VAKGGKEILL SADHIIIATG GRPRYPTHIE GALEYGITSD DIFWLKESPG KTLVVGASYV ALECAGFLTG IGLDTTIMMR SIPLRGFDQQ MSSMVIEHMA SHGTRFLRGC APSRVRRLPD GQLQVTWEDS TTGKEDTGTF D
- 交叉反应
- 人, 小鼠
- 产品特性
- Polyclonal Antibodies
- 免疫原
- Recombinant fusion protein containing a sequence corresponding to amino acids 100-310 of human Thioredoxin reductase 2 (Thioredoxin reductase 2 (TXNRD2 ) ) (NP_006431.2).
- 亚型
- IgG
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- 应用备注
- WB,1:500 - 1:2000,IHC,1:50 - 1:200,IF,1:50 - 1:200
- 说明
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HIGH QUALITY
- 限制
- 仅限研究用
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- 状态
- Liquid
- 缓冲液
- PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- -20 °C
- 储存方法
- Store at -20°C. Avoid freeze / thaw cycles.
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- 抗原
- TXNRD2 (Thioredoxin Reductase 2 (TXNRD2))
- 别名
- TXNRD2 (TXNRD2 产品)
- 别名
- CG11401 antibody, Dm-TrxR antibody, DmTrx antibody, DmTrxR-2 antibody, Dmel\\CG11401 antibody, Trxr2 antibody, trxr-2 antibody, SELZ antibody, TR antibody, TR-BETA antibody, TR3 antibody, TRXR2 antibody, AA118373 antibody, ESTM573010 antibody, TGR antibody, Tr3 antibody, Trxrd2 antibody, thioredoxin reductase 2 antibody, Trxr-2 antibody, TXNRD2 antibody, Txnrd2 antibody
- 背景
- The protein encoded by this gene belongs to the pyridine nucleotide-disulfide oxidoreductase family, and is a member of the thioredoxin (Trx) system. Three thioredoxin reductase (TrxR) isozymes are found in mammals. TrxRs are selenocysteine-containing flavoenzymes, which reduce thioredoxins, as well as other substrates, and play a key role in redox homoeostasis. This gene encodes a mitochondrial form important for scavenging reactive oxygen species in mitochondria. It functions as a homodimer containing FAD, and selenocysteine (Sec) at the active site. Sec is encoded by UGA codon that normally signals translation termination. The 3' UTRs of selenoprotein mRNAs contain a conserved stem-loop structure, the Sec insertion sequence (SECIS) element, which is necessary for the recognition of UGA as a Sec codon rather than as a stop signal. Alternatively spliced transcript variants encoding different isoforms, including a few localized in the cytosol and some lacking the C-terminal Sec residue, have been found for this gene.,TXNRD2,SELZ,TR,TR-BETA,TR3,TRXR2,Cell Biology & Developmental Biology,Endocrine & Metabolism,TXNRD2
- 分子量
- 30 kDa/46 kDa/53 kDa/56 kDa
- 基因ID
- 10587
- UniProt
- Q9NNW7
- 途径
- Cell RedoxHomeostasis
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