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- 抗原 See all TP53INP1 抗体
- TP53INP1 (Tumor Protein P53 Inducible Nuclear Protein 1 (TP53INP1))
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抗原表位
- AA 1-100
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适用
- 人
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This TP53INP1 antibody is un-conjugated
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应用范围
- Western Blotting (WB)
- 序列
- MFQRLNKMFV GEVSSSSNQE PEFNEKEDDE WILVDFIDTC TGFSAEEEEE EEDISEESPT EHPSVFSCLP ASLECLADTS DSCFLQFESC PMEESWFITP
- 交叉反应
- 小鼠
- 产品特性
- Polyclonal Antibodies
- 免疫原
- A synthetic peptide corresponding to a sequence within amino acids 1-100 of human p53 DINP1 (NP_001129205.1).
- 亚型
- IgG
- Top Product
- Discover our top product TP53INP1 Primary Antibody
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anti-Tumor Protein P53 Inducible Nuclear Protein 1 (TP53INP1) (AA 138-205) antibody
TP53INP1 适用: 人 ELISA, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Tumor Protein P53 Inducible Nuclear Protein 1 (TP53INP1) (Internal Region) antibodyTP53INP1 适用: 人, 小鼠 WB, ELISA, IHC, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-Tumor Protein P53 Inducible Nuclear Protein 1 (TP53INP1) (AA 36-64), (N-Term) antibodyTP53INP1 适用: 人 WB, IHC (p) 宿主: 兔 Polyclonal RB29674 unconjugated
anti-Tumor Protein P53 Inducible Nuclear Protein 1 (TP53INP1) (AA 181-210), (C-Term) antibodyTP53INP1 适用: 小鼠 WB, IHC (p) 宿主: 兔 Polyclonal RB29563 unconjugated
anti-Tumor Protein P53 Inducible Nuclear Protein 1 (TP53INP1) (N-Term) antibodyTP53INP1 适用: 人, 小鼠, 大鼠 WB, IHC (p), EIA 宿主: 兔 Polyclonal unconjugated
anti-Tumor Protein P53 Inducible Nuclear Protein 1 (TP53INP1) (C-Term) antibodyTP53INP1 适用: 人 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Tumor Protein P53 Inducible Nuclear Protein 1 (TP53INP1) (AA 43-72), (N-Term) antibodyTP53INP1 适用: 人 WB, IHC (p), EIA 宿主: 兔 Polyclonal unconjugated
anti-Tumor Protein P53 Inducible Nuclear Protein 1 (TP53INP1) (AA 188-218), (C-Term) antibodyTP53INP1 适用: 人, 小鼠 WB, IHC (p), EIA 宿主: 兔 Polyclonal unconjugated
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- 应用备注
- WB,1:500 - 1:2000
- 限制
- 仅限研究用
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- 状态
- Liquid
- 缓冲液
- PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- -20 °C
- 储存方法
- Store at -20°C. Avoid freeze / thaw cycles.
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- 抗原
- TP53INP1 (Tumor Protein P53 Inducible Nuclear Protein 1 (TP53INP1))
- 别名
- TP53INP1 (TP53INP1 产品)
- 别名
- cb1036 antibody, wu:fb70a09 antibody, wu:fi13h08 antibody, zgc:158431 antibody, TP53INP1 antibody, 2700057G22Rik antibody, SIP antibody, SIP18 antibody, SIP27 antibody, Stinp antibody, Teap antibody, TP53DINP1 antibody, TP53INP1A antibody, TP53INP1B antibody, p53DINP1 antibody, Trp53inp1 antibody, tumor protein p53 inducible nuclear protein 1 antibody, tumor protein p53 inducible nuclear protein 1 S homeolog antibody, transformation related protein 53 inducible nuclear protein 1 antibody, TP53INP1 antibody, tp53inp1.S antibody, tp53inp1 antibody, Trp53inp1 antibody, Tp53inp1 antibody
- 背景
- Antiproliferative and proapoptotic protein involved in cell stress response which acts as a dual regulator of transcription and autophagy. Acts as a positive regulator of autophagy. In response to cellular stress or activation of autophagy, relocates to autophagosomes where it interacts with autophagosome-associated proteins GABARAP, GABARAPL1/L2, MAP1LC3A/B/C and regulates autophagy. Acts as an antioxidant and plays a major role in p53/TP53-driven oxidative stress response. Possesses both a p53/TP53-independent intracellular reactive oxygen species (ROS regulatory function and a p53/TP53-dependent transcription regulatory function. Positively regulates p53/TP53 and p73/TP73 and stimulates their capacity to induce apoptosis and regulate cell cycle. In response to double-strand DNA breaks, promotes p53/TP53 phosphorylation on 'Ser-46' and subsequent apoptosis. Acts as a tumor suppressor by inducing cell death by an autophagy and caspase-dependent mechanism. Can reduce cell migration by regulating the expression of SPARC.,TP53INP1,SIP,TP53DINP1,TP53INP1A,TP53INP1B,Teap,p53DINP1,Cancer,Tumor suppressors,p53 pathway,Cell Biology & Developmental Biology,Apoptosis,Autophagy,TP53INP1
- 分子量
- 18 kDa/27 kDa
- 基因ID
- 94241
- UniProt
- Q96A56
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