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背景
Guanyl-nucleotide exchange factor that activates RHO-like proteins and connects extracellular signals to cytoskeletal activities. Activates RAC1, CDC42, and to a lesser extent RHOA and their downstream signaling to regulate processes like cell adhesion and cell migration.,TIAM1,Signal Transduction,G protein signaling,Cell Biology & Developmental Biology,Cytoskeleton,Actins,TIAM1