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TBC1D23 抗体 (AA 250-600)

TBC1D23 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN6148882
发货至: 中国
  • 抗原 See all TBC1D23 products
    TBC1D23 (TBC1 Domain Family, Member 23 (TBC1D23))
    抗原表位
    • 4
    • 1
    • 1
    • 1
    AA 250-600
    适用
    • 9
    • 3
    • 3
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    宿主
    • 9
    克隆类型
    • 9
    多克隆
    标记
    • 6
    • 1
    • 1
    • 1
    This TBC1D23 antibody is un-conjugated
    应用范围
    • 5
    • 5
    • 4
    • 2
    • 1
    • 1
    Western Blotting (WB)
    序列
    SDSKEEVIKF LENTPSSLNI EDIEDLFSLA QYYCSKTPAS FRKDNHHLFG STLLGIKDDD ADLSQALCLA ISVSEILQAN QLQGEGVRFF VVDCRPAEQY NAGHLSTAFH LDSDLMLQNP SEFAQSVKSL LEAQKQSIES GSIAGGEHLC FMGSGREEED MYMNMVLAHF LQKNKEYVSI ASGGFMALQQ HLADINVDGP ENGYGHWIAS TSGSRSSINS VDGESPNGSS DRGMKSLVNK MTVALKTKSV NVREKVISFI ENTSTPVDRM SFNLPWPDRS CTERHVSSSD RVGKPYRGVK PVFSIGDEEE YDTDEIDSSS MSDDDRKEVV NIQTWINKPD VKHHFPCKEV K
    交叉反应
    人, 小鼠
    产品特性
    Polyclonal Antibodies
    免疫原
    Recombinant fusion protein containing a sequence corresponding to amino acids 250-600 of human TBC1D23 (NP_001186127.1).
    亚型
    IgG
  • 应用备注
    WB,1:500 - 1:2000
    限制
    仅限研究用
  • 状态
    Liquid
    缓冲液
    PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    -20 °C
    储存方法
    Store at -20°C. Avoid freeze / thaw cycles.
  • 抗原
    TBC1D23 (TBC1 Domain Family, Member 23 (TBC1D23))
    别名
    TBC1D23 (TBC1D23 产品)
    别名
    RGD1307925 antibody, NS4ATP1 antibody, 4930451A13Rik antibody, AU015720 antibody, AU043671 antibody, AU043778 antibody, D030022P07Rik antibody, W51689 antibody, zgc:63756 antibody, TBC1 domain family, member 23 antibody, TBC1 domain family member 23 antibody, Tbc1d23 antibody, TBC1D23 antibody, tbc1d23 antibody
    背景
    Putative Rab GTPase-activating protein which plays a role in vesicular trafficking. Involved in endosome-to-Golgi trafficking. Acts as a bridging protein by binding simultaneously to golgins, including GOLGA1 and GOLGA4, located at the trans-Golgi, and to the WASH complex, located on endosome-derived vesicles. Together with WDR11 complex facilitates the golgin-mediated capture of vesicles generated using AP-1. Plays a role in brain development, including in cortical neuron positioning (By similarity. May also be important for neurite outgrowth, possibly through its involvement in membrane trafficking and cargo delivery, 2 processes that are essential for axonal and dendritic growth (By similarity. May act as a general inhibitor of innate immunity signaling, strongly inhibiting multiple TLR and dectin/CLEC7A-signaling pathways. Does not alter initial activation events, but instead affects maintenance of inflammatory gene expression several hours after bacterial lipopolysaccharide (LPS challenge (By similarity.,TBC1D23,NS4ATP1,TBC1D23
    分子量
    76 kDa/78 kDa
    基因ID
    55773
    UniProt
    Q9NUY8
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