Nesprin3 抗体 (AA 740-920)
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- 抗原 See all Nesprin3 (C14orf49) 抗体
- Nesprin3 (C14orf49) (Chromosome 14 Open Reading Frame 49 (C14orf49))
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抗原表位
- AA 740-920
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适用
- 人
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This Nesprin3 antibody is un-conjugated
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应用范围
- Western Blotting (WB), Immunofluorescence (IF)
- 序列
- LRLLEESLLS LIRNWHLQRM EVDSGKKMVF TNNIPKSGFL INPMDPIPRH RRRANLLQEE EGSHEDFSQL LRNFGQWLQV ENSKLVRIIA MRTSTAEDLR TRKSKLQELE ARVPEGQHLF ENLLRLGPAR GTSDELEDLR YQWMLYKSKL KDSGHLLTQS SPGEPTGFQK TRRWRGLGSL F
- 交叉反应
- 人, 小鼠
- 产品特性
- Polyclonal Antibodies
- 免疫原
- Recombinant fusion protein containing a sequence corresponding to amino acids 740-920 of human SYNE3 (NP_689805.3).
- 亚型
- IgG
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- 应用备注
- WB,1:500 - 1:2000,IF,1:50 - 1:200
- 说明
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HIGH QUALITY
- 限制
- 仅限研究用
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- 状态
- Liquid
- 缓冲液
- PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- -20 °C
- 储存方法
- Store at -20°C. Avoid freeze / thaw cycles.
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- 抗原
- Nesprin3 (C14orf49) (Chromosome 14 Open Reading Frame 49 (C14orf49))
- 别名
- SYNE3 (C14orf49 产品)
- 别名
- C14orf49 antibody, NET53 antibody, Nesp3 antibody, 4831426I19Rik antibody, nesprin-3 antibody, spectrin repeat containing nuclear envelope family member 3 antibody, spectrin repeat containing, nuclear envelope family member 3 antibody, SYNE3 antibody, Syne3 antibody
- 背景
- As a component of the LINC (LInker of Nucleoskeleton and Cytoskeleton complex involved in the connection between the nuclear lamina and the cytoskeleton. The nucleocytoplasmic interactions established by the LINC complex play an important role in the transmission of mechanical forces across the nuclear envelope and in nuclear movement and positioning. Probable anchoring protein which tethers the nucleus to the cytoskeleton by binding PLEC which can associate with the intermediate filament system. Plays a role in the regulation of aortic epithelial cell morphology, and is required for flow-induced centrosome polarization and directional migration in aortic endothelial cells.,SYNE3,C14orf139,C14orf49,KASH3,LINC00341,NCRNA00341,NET53,Nesp3,nesprin-3,Signal Transduction,Cell Biology & Developmental Biology,Cytoskeleton,Microfilaments,SYNE3
- 分子量
- 68 kDa/111 kDa/112 kDa
- 基因ID
- 161176
- UniProt
- Q6ZMZ3
- 途径
- Maintenance of Protein Location
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