C10orf94 antibody, CT76 antibody, 4933406J07Rik antibody, synaptonemal complex central element protein 1 antibody, SYCE1 antibody, Syce1 antibody
背景
This gene encodes a member of the synaptonemal complex, which links homologous chromosomes during prophase I of meiosis. The tripartite structure of the complex is highly conserved amongst metazoans. It consists of two lateral elements and a central region formed by transverse elements and a central element. The protein encoded by this gene localizes to the central element and is required for initiation and elongation of the synapsis. Allelic variants of this gene have been associated with premature ovarian failure and spermatogenic failure. Alternative splicing results in multiple transcript variants.,SYCE1,C10orf94,CT76,POF12,SPGF15,Epigenetics & Nuclear Signaling,Cell Biology & Developmental Biology,Apoptosis,Cell Cycle,SYCE1