SUPV3L1 抗体 (AA 577-786)
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- 抗原 See all SUPV3L1 抗体
- SUPV3L1 (Suppressor of Var1, 3-Like 1 (SUPV3L1))
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抗原表位
- AA 577-786
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适用
- 人
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This SUPV3L1 antibody is un-conjugated
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应用范围
- Western Blotting (WB), Immunofluorescence (IF), Immunohistochemistry (IHC)
- 序列
- APINKKQPFV CSSLLQFARQ YSRNEPLTFA WLRRYIKWPL LPPKNIKDLM DLEAVHDVLD LYLWLSYRFM DMFPDASLIR DLQKELDGII QDGVHNITKL IKMSETHKLL NLEGFPSGSQ SRLSGTLKSQ ARRTRGTKAL GSKATEPPSP DAGELSLASR LVQQGLLTPD MLKQLEKEWM TQQTEHNKEK TESGTHPKGT RRKKKEPDSD
- 交叉反应
- 人, 小鼠, 大鼠
- 产品特性
- Polyclonal Antibodies
- 免疫原
- Recombinant fusion protein containing a sequence corresponding to amino acids 577-786 of human SUPV3L1 (NP_003162.2).
- 亚型
- IgG
- Top Product
- Discover our top product SUPV3L1 Primary Antibody
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- 应用备注
- WB,1:1000 - 1:4000,IHC,1:50 - 1:200,IF,1:50 - 1:200
- 说明
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HIGH QUALITY
- 限制
- 仅限研究用
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- 状态
- Liquid
- 缓冲液
- PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- -20 °C
- 储存方法
- Store at -20°C. Avoid freeze / thaw cycles.
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- 抗原
- SUPV3L1 (Suppressor of Var1, 3-Like 1 (SUPV3L1))
- 别名
- SUPV3L1 (SUPV3L1 产品)
- 背景
- Major helicase player in mitochondrial RNA metabolism. Component of the mitochondrial degradosome (mtEXO complex, that degrades 3' overhang double-stranded RNA with a 3'-to-5' directionality in an ATP-dependent manner. Involved in the degradation of non-coding mitochondrial transcripts (MT-ncRNA and tRNA-like molecules. ATPase and ATP-dependent multisubstrate helicase, able to unwind double-stranded (ds DNA and RNA, and RNA/DNA heteroduplexes in the 5'-to-3' direction. Plays a role in the RNA surveillance system in mitochondria, regulates the stability of mature mRNAs, the removal of aberrantly formed mRNAs and the rapid degradation of non coding processing intermediates. Also implicated in recombination and chromatin maintenance pathways. May protect cells from apoptosis. Associates with mitochondrial DNA.,SUPV3L1,SUV3,Epigenetics & Nuclear Signaling,RNA Binding,Cell Biology & Developmental Biology,Apoptosis,Endocrine & Metabolism,Mitochondrial metabolism,SUPV3L1
- 分子量
- 87 kDa
- 基因ID
- 6832
- UniProt
- Q8IYB8
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