电话:
+86 (0512) 65829739
传真:
+86 (010) 6788 5057
电子邮件:
orders@antibodies-online.cn

SMPD3 抗体 (AA 416-655)

SMPD3 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN6148146
发货至: 中国
  • 抗原 See all SMPD3 抗体
    SMPD3 (Sphingomyelin Phosphodiesterase 3 (SMPD3))
    抗原表位
    • 14
    • 7
    • 5
    • 4
    • 1
    • 1
    AA 416-655
    适用
    • 28
    • 4
    • 4
    • 1
    • 1
    • 1
    • 1
    • 1
    宿主
    • 25
    • 2
    • 1
    克隆类型
    • 28
    多克隆
    标记
    • 14
    • 4
    • 3
    • 3
    • 2
    • 2
    This SMPD3 antibody is un-conjugated
    应用范围
    • 22
    • 17
    • 2
    • 1
    Western Blotting (WB)
    序列
    MDVAYHCYPN KCNDDALASK GALFLKVQVG STPQDQRIVG YIACTHLHAP QEDSAIRCGQ LDLLQDWLAD FRKSTSSSSA ANPEELVAFD VVCGDFNFDN CSSDDKLEQQ HSLFTHYRDP CRLGPGEEKP WAIGTLLDTN GLYDEDVCTP DNLQKVLESE EGRREYLAFP TSKSSGQKGR KELLKGNGRR IDYMLHAEEG LCPDWKAEVE EFSFITQLSG LTDHLPVAMR LMVSSGEEEA
    交叉反应
    人, 小鼠, 大鼠
    产品特性
    Polyclonal Antibodies
    免疫原
    Recombinant fusion protein containing a sequence corresponding to amino acids 416-655 of human SMPD3 (NP_061137.1).
    亚型
    IgG
    Top Product
    Discover our top product SMPD3 Primary Antibody
  • 应用备注
    WB,1:1000 - 1:3000
    限制
    仅限研究用
  • 状态
    Liquid
    缓冲液
    PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    -20 °C
    储存方法
    Store at -20°C. Avoid freeze / thaw cycles.
  • 抗原
    SMPD3 (Sphingomyelin Phosphodiesterase 3 (SMPD3))
    别名
    SMPD3 (SMPD3 产品)
    别名
    4631433G07Rik antibody, AI427456 antibody, AW537966 antibody, fro antibody, nSMase2 antibody, cca1 antibody, NSMASE2 antibody, sphingomyelin phosphodiesterase 3 antibody, sphingomyelin phosphodiesterase 3, neutral antibody, SMPD3 antibody, Smpd3 antibody
    背景
    Catalyzes the hydrolysis of sphingomyelin to form ceramide and phosphocholine. Ceramide mediates numerous cellular functions, such as apoptosis and growth arrest, and is capable of regulating these 2 cellular events independently. Also hydrolyzes sphingosylphosphocholine. Regulates the cell cycle by acting as a growth suppressor in confluent cells. Probably acts as a regulator of postnatal development and participates in bone and dentin mineralization. Binds to anionic phospholipids (APLs such as phosphatidylserine (PS and phosphatidic acid (PA that modulate enzymatic activity and subcellular location. May be involved in IL-1-beta-induced JNK activation in hepatocytes (By similarity. May act as a mediator in transcriptional regulation of NOS2/iNOS via the NF-kappa-B activation under inflammatory conditions (By similarity.,SMPD3,NSMASE2,Cell Biology & Developmental Biology,Apoptosis,Neuroscience,Cell Type Marker,Neurodegenerative Diseases,Amyloid Plaque and Neurofibrillary Tangle Formation in Alzheimer's Disease,Oligodendrocyte marker,Neuron marker,SMPD3
    分子量
    70 kDa/71 kDa
    基因ID
    55512
    UniProt
    Q9NY59
    途径
    Hormone Transport
You are here:
客服