SMN2 抗体 (AA 1-197)
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- 抗原 See all SMN2 抗体
- SMN2 (Survival of Motor Neuron 2, Centromeric (SMN2))
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抗原表位
- AA 1-197
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适用
- 人
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This SMN2 antibody is un-conjugated
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应用范围
- Western Blotting (WB), Immunofluorescence (IF), Immunoprecipitation (IP)
- 序列
- MAMSSGGSGG GVPEQEDSVL FRRGTGQSDD SDIWDDTALI KAYDKAVASF KHALKNGDIC ETSGKPKTTP KRKPAKKNKS QKKNTAASLQ QWKVGDKCSA IWSEDGCIYP ATIASIDFKR ETCVVVYTGY GNREEQNLSD LLSPICEVAN NIEQNAQENE NESQVSTDES ENSRSPGNKS DNIKPKSAPW NSFLPPP
- 交叉反应
- 人, 小鼠, 大鼠
- 产品特性
- Polyclonal Antibodies
- 免疫原
- Recombinant fusion protein containing a sequence corresponding to amino acids 1-197 of human SMN2 (NP_059107.1).
- 亚型
- IgG
- Top Product
- Discover our top product SMN2 Primary Antibody
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anti-Survival of Motor Neuron 2, Centromeric (SMN2) (AA 1-282) antibody
SMN2 适用: 人 WB, IF, ELISA, IHC (p) 宿主: 小鼠 Monoclonal 2B11-2A9 unconjugated
anti-Survival of Motor Neuron 2, Centromeric (SMN2) (AA 16-251) antibodySMN2 适用: 人 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Survival of Motor Neuron 2, Centromeric (SMN2) antibodySMN2 适用: 人, 小鼠, 大鼠 IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Survival of Motor Neuron 2, Centromeric (SMN2) (AA 1-282) antibodySMN2 适用: 人 WB, IF 宿主: 小鼠 Polyclonal unconjugated
anti-Survival of Motor Neuron 2, Centromeric (SMN2) (AA 1-197) antibodySMN2 适用: 人 WB, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Survival of Motor Neuron 2, Centromeric (SMN2) (AA 191-294) antibodySMN2 适用: 人 WB, ELISA 宿主: 小鼠 Polyclonal unconjugated
anti-Survival of Motor Neuron 2, Centromeric (SMN2) (AA 1-282) antibodySMN2 适用: 人 IP 宿主: 兔 Polyclonal unconjugated
anti-Survival of Motor Neuron 2, Centromeric (SMN2) (AA 1-294) antibodySMN2 适用: 人 WB 宿主: 小鼠 Polyclonal unconjugated
anti-Survival of Motor Neuron 2, Centromeric (SMN2) (N-Term) antibodySMN2 适用: 人, 小鼠, Pig, 兔, 犬, 山羊, 马 WB 宿主: 兔 Polyclonal unconjugated
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- 应用备注
- WB,1:500 - 1:2000,IF,1:50 - 1:200,IP,1:20 - 1:50
- 说明
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HIGH QUALITY
- 限制
- 仅限研究用
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- 状态
- Liquid
- 缓冲液
- PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- -20 °C
- 储存方法
- Store at -20°C. Avoid freeze / thaw cycles.
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- 抗原
- SMN2 (Survival of Motor Neuron 2, Centromeric (SMN2))
- 别名
- SMN2 (SMN2 产品)
- 别名
- BCD541 antibody, C-BCD541 antibody, GEMIN1 antibody, SMNC antibody, TDRD16B antibody, bcd541 antibody, c-bcd541 antibody, gemin-1 antibody, smn2 antibody, smnc antibody, survival of motor neuron 2, centromeric antibody, survival of motor neuron 2, centromeric L homeolog antibody, SMN2 antibody, smn2.L antibody
- 背景
- This gene is part of a 500 kb inverted duplication on chromosome 5q13. This duplicated region contains at least four genes and repetitive elements which make it prone to rearrangements and deletions. The telomeric and centromeric copies of this gene are nearly identical and encode the same protein. While mutations in the telomeric copy are associated with spinal muscular atrophy, mutations in this gene, the centromeric copy, do not lead to disease. The critical sequence difference between the two genes is a single nucleotide in exon 7, which is thought to be an exon splice enhancer. Note that the nine exons of both the telomeric and centromeric copies are designated historically as exon 1, 2a, 2b, and 3-8. It is thought that gene conversion events may involve the two genes, leading to varying copy numbers of each gene. The full length protein encoded by this gene localizes to both the cytoplasm and the nucleus. Within the nucleus, the protein localizes to subnuclear bodies called gems which are found near coiled bodies containing high concentrations of small ribonucleoproteins (snRNPs). This protein forms heteromeric complexes with proteins such as SIP1 and GEMIN4, and also interacts with several proteins known to be involved in the biogenesis of snRNPs, such as hnRNP U protein and the small nucleolar RNA binding protein. Four transcript variants encoding distinct isoforms have been described.,SMN2,BCD541,C-BCD541,GEMIN1,SMNC,TDRD16B,SMN2
- 分子量
- 27 kDa/28 kDa/30 kDa/31 kDa
- 基因ID
- 6607
- UniProt
- Q16637
- 途径
- Ribonucleoprotein Complex Subunit Organization
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