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- 抗原 See all SKP2 抗体
- SKP2 (S-Phase Kinase-Associated Protein 2 (SKP2))
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抗原表位
- AA 1-100
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适用
- 人
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This SKP2 antibody is un-conjugated
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应用范围
- Western Blotting (WB), Immunofluorescence (IF)
- 序列
- MHRKHLQEIP DLSSNVATSF TWGWDSSKTS ELLSGMGVSA LEKEEPDSEN IPQELLSNLG HPESPPRKRL KSKGSDKDFV IVRRPKLNRE NFPGVSWDSL
- 交叉反应
- 人, 小鼠, 大鼠
- 产品特性
- Polyclonal Antibodies
- 免疫原
- A synthetic peptide corresponding to a sequence within amino acids 1-100 of human SKP2 (NP_005974.2).
- 亚型
- IgG
- Top Product
- Discover our top product SKP2 Primary Antibody
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- 应用备注
- WB,1:500 - 1:2000,IF,1:50 - 1:200
- 限制
- 仅限研究用
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- 状态
- Liquid
- 缓冲液
- PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- -20 °C
- 储存方法
- Store at -20°C. Avoid freeze / thaw cycles.
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Upregulation of Cdh1 Attenuates Isoflurane-Induced Neuronal Apoptosis and Long-Term Cognitive Impairments in Developing Rats." in: Frontiers in cellular neuroscience, Vol. 11, pp. 368, (2017) (PubMed).
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Upregulation of Cdh1 Attenuates Isoflurane-Induced Neuronal Apoptosis and Long-Term Cognitive Impairments in Developing Rats." in: Frontiers in cellular neuroscience, Vol. 11, pp. 368, (2017) (PubMed).
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- 抗原
- SKP2 (S-Phase Kinase-Associated Protein 2 (SKP2))
- 别名
- SKP2 (SKP2 产品)
- 别名
- FBXL1 antibody, FBL1 antibody, FLB1 antibody, p45 antibody, RGD1562456 antibody, S-phase kinase-associated protein 2 (p45) antibody, S-phase kinase associated protein 2 antibody, Skp2 antibody, SKP2 antibody
- 背景
- This gene encodes a member of the F-box protein family which is characterized by an approximately 40 amino acid motif, the F-box. The F-box proteins constitute one of the four subunits of ubiquitin protein ligase complex called SCFs (SKP1-cullin-F-box), which function in phosphorylation-dependent ubiquitination. The F-box proteins are divided into 3 classes: Fbws containing WD-40 domains, Fbls containing leucine-rich repeats, and Fbxs containing either different protein-protein interaction modules or no recognizable motifs. The protein encoded by this gene belongs to the Fbls class, in addition to an F-box, this protein contains 10 tandem leucine-rich repeats. This protein is an essential element of the cyclin A-CDK2 S-phase kinase. It specifically recognizes phosphorylated cyclin-dependent kinase inhibitor 1B (CDKN1B, also referred to as p27 or KIP1) predominantly in S phase and interacts with S-phase kinase-associated protein 1 (SKP1 or p19). In addition, this gene is established as a protooncogene causally involved in the pathogenesis of lymphomas. Alternative splicing of this gene generates three transcript variants encoding different isoforms.,SKP2,FBL1,FBXL1,FLB1,p45,Signal Transduction,Kinase,Cell Biology & Developmental Biology,Apoptosis,Ubiquitin,Ubiquitin-Proteasome Signaling Pathway,SKP2
- 分子量
- 23 kDa/46 kDa/47 kDa
- 基因ID
- 6502
- UniProt
- Q13309
- 途径
- Mitotic G1-G1/S Phases
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