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SKIL 抗体 (AA 420-684)
SKIL
适用: 人
WB
宿主: 兔
Polyclonal
unconjugated
SKIL抗体详情
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抗原
See all SKIL 抗体
SKIL
(SKI-Like Oncogene (SKIL))
抗原表位
All epitopes for SKIL 抗体
AA 420-684
适用
All reactivities for SKIL 抗体
人
宿主
All hosts for SKIL 抗体
兔
克隆类型
All clonalities for SKIL 抗体
多克隆
标记
All conjugates for SKIL 抗体
This SKIL antibody is un-conjugated
应用范围
All applications for SKIL 抗体
Western Blotting (WB)
序列
SQSKELTKTE ASKSISRQSE KAHSSGKLQK TVSYPDVSLE EQEKMDLKTS RELCSRLDAS ISNNSTSKRK SESATCNLVR DINKVGIGLV AAASSPLLVK DVICEDDKGK IMEEVMRTYL KQQEKLNLIL QKKQQLQMEV KMLSSSKSMK ELTEEQQNLQ KELESLQNEH AQRMEEFYVE QKDLEKKLEQ IMKQKCTCDS NLEKDKEAEY AGQLAELRQR LDHAEADRQE LQDELRQERE ARQKLEMMIK ELKLQILKSS KTAKE
交叉反应
人, 小鼠, 大鼠
产品特性
Polyclonal Antibodies
免疫原
Recombinant fusion protein containing a sequence corresponding to amino acids 420-684 of human SKIL (NP_001234937.1).
亚型
IgG
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使用细节
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应用备注
WB,1:500 - 1:2000
限制
仅限研究用
贮存及处理
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状态
Liquid
缓冲液
PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.
储存液
Sodium azide
注意事项
This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
储存条件
-20 °C
储存方法
Store at -20°C. Avoid freeze / thaw cycles.
SKIL目标详情
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抗原
SKIL
(SKI-Like Oncogene (SKIL))
别名
SKIL (SKIL 产品 )
别名
SNO antibody, SnoA antibody, SnoI antibody, SnoN antibody, Skir antibody, Sno antibody, SKIL antibody, DKFZp459L122 antibody, sno antibody, zgc:193698 antibody, SKI like proto-oncogene antibody, SKI-like proto-oncogene antibody, ski-like protein antibody, SKI-like antibody, SKI-like proto-oncogene b antibody, SKIL antibody, Skil antibody, LOC100010058 antibody, skil antibody, skilb antibody
背景
The protein encoded by this gene is a component of the SMAD pathway, which regulates cell growth and differentiation through transforming growth factor-beta (TGFB). In the absence of ligand, the encoded protein binds to the promoter region of TGFB-responsive genes and recruits a nuclear repressor complex. TGFB signaling causes SMAD3 to enter the nucleus and degrade this protein, allowing these genes to be activated. Four transcript variants encoding three different isoforms have been found for this gene.,SKIL,SNO,SnoA,SnoI,SnoN,Epigenetics & Nuclear Signaling,Cancer,Tumor suppressors,Target gene,SKIL
分子量
44 kDa/46 kDa/71 kDa/74 kDa/76 kDa
基因ID
6498
UniProt
P12757
途径
Positive Regulation of Response to DNA Damage Stimulus
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