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SIRT1 抗体 (AA 448-747)

SIRT1 适用: 人 WB, IHC, IP, IF 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN6147784
发货至: 中国
  • 抗原 See all SIRT1 抗体
    SIRT1 (Sirtuin 1 (SIRT1))
    抗原表位
    • 31
    • 16
    • 16
    • 8
    • 8
    • 6
    • 6
    • 6
    • 5
    • 4
    • 3
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 448-747
    适用
    • 145
    • 88
    • 60
    • 34
    • 5
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    宿主
    • 129
    • 20
    • 2
    • 2
    • 1
    克隆类型
    • 117
    • 37
    多克隆
    标记
    • 64
    • 13
    • 10
    • 4
    • 4
    • 4
    • 4
    • 4
    • 4
    • 4
    • 4
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 1
    • 1
    This SIRT1 antibody is un-conjugated
    应用范围
    • 115
    • 50
    • 47
    • 41
    • 39
    • 34
    • 21
    • 21
    • 17
    • 13
    • 9
    • 4
    • 4
    • 3
    • 2
    • 1
    • 1
    • 1
    Western Blotting (WB), Immunohistochemistry (IHC), Immunoprecipitation (IP), Immunofluorescence (IF)
    序列
    VALIPSSIPH EVPQILINRE PLPHLHFDVE LLGDCDVIIN ELCHRLGGEY AKLCCNPVKL SEITEKPPRT QKELAYLSEL PPTPLHVSED SSSPERTSPP DSSVIVTLLD QAAKSNDDLD VSESKGCMEE KPQEVQTSRN VESIAEQMEN PDLKNVGSST GEKNERTSVA GTVRKCWPNR VAKEQISRRL DGNQYLFLPP NRYIFHGAEV YSDSEDDVLS SSSCGSNSDS GTCQSPSLEE PMEDESEIEE FYNGLEDEPD VPERAGGAGF GTDGDDQEAI NEAISVKQEV TDMNYPSNKS
    交叉反应
    人, 小鼠, 大鼠
    产品特性
    Polyclonal Antibodies
    免疫原
    Recombinant fusion protein containing a sequence corresponding to amino acids 448-747 of human SIRT1 (NP_036370.2).
    亚型
    IgG
    Top Product
    Discover our top product SIRT1 Primary Antibody
  • 应用备注
    WB,1:500 - 1:2000,IHC,1:50 - 1:200,IF,1:50 - 1:200,IP,1:50 - 1:200
    说明

    HIGH QUALITY

    限制
    仅限研究用
  • 状态
    Liquid
    缓冲液
    PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    -20 °C
    储存方法
    Store at -20°C. Avoid freeze / thaw cycles.
  • 抗原
    SIRT1 (Sirtuin 1 (SIRT1))
    别名
    SIRT1 (SIRT1 产品)
    别名
    sirtuin 1 antibody, AA673258 antibody, SIR2L1 antibody, Sir2 antibody, Sir2a antibody, Sir2alpha antibody, sir2l1 antibody, sirtuin antibody, SIR2 antibody, sirtuin 1 antibody, sirtuin 1 L homeolog antibody, SIRT1 antibody, SRT1 antibody, Sirt1 antibody, sirt1.L antibody
    背景
    This gene encodes a member of the sirtuin family of proteins, homologs to the yeast Sir2 protein. Members of the sirtuin family are characterized by a sirtuin core domain and grouped into four classes. The functions of human sirtuins have not yet been determined, however, yeast sirtuin proteins are known to regulate epigenetic gene silencing and suppress recombination of rDNA. Studies suggest that the human sirtuins may function as intracellular regulatory proteins with mono-ADP-ribosyltransferase activity. The protein encoded by this gene is included in class I of the sirtuin family. Alternative splicing results in multiple transcript variants.,SIR2,SIR2L1,SIR2alpha,SIRT1,sirtuin 1,Epigenetics & Nuclear Signaling,Chromatin Modifying Enzymes,Deacetylation,Cell Biology & Developmental Biology,Apoptosis,Endocrine & Metabolism,Mitochondrial metabolism,AMPK Signaling Pathway,SIRT1
    分子量
    61 kDa/81 kDa
    基因ID
    23411
    UniProt
    Q96EB6
    途径
    MAPK Pathway, Intracellular Steroid Hormone Receptor Signaling Pathway, Regulation of Intracellular Steroid Hormone Receptor Signaling, Carbohydrate Homeostasis, Positive Regulation of Endopeptidase Activity, Regulation of Carbohydrate Metabolic Process, Positive Regulation of Response to DNA Damage Stimulus, Negative Regulation of intrinsic apoptotic Signaling
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