SIRPA 抗体 (AA 395-504)
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- 抗原 See all SIRPA 抗体
- SIRPA (Signal-Regulatory Protein alpha (SIRPA))
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抗原表位
- AA 395-504
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适用
- 人
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This SIRPA antibody is un-conjugated
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应用范围
- Western Blotting (WB), Immunofluorescence (IF)
- 序列
- RIRQKKAQGS TSSTRLHEPE KNAREITQDT NDITYADLNL PKGKKPAPQA AEPNNHTEYA SIQTSPQPAS EDTLTYADLD MVHLNRTPKQ PAPKPEPSFS EYASVQVPRK
- 交叉反应
- 人, 小鼠, 大鼠
- 产品特性
- Polyclonal Antibodies
- 免疫原
- Recombinant fusion protein containing a sequence corresponding to amino acids 395-504 of human CD172a/SIRPalpha (NP_542970.1).
- 亚型
- IgG
- Top Product
- Discover our top product SIRPA Primary Antibody
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- 应用备注
- WB,1:500 - 1:2000,IF,1:50 - 1:200
- 说明
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HIGH QUALITY
- 限制
- 仅限研究用
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- 状态
- Liquid
- 缓冲液
- PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- -20 °C
- 储存方法
- Store at -20°C. Avoid freeze / thaw cycles.
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- 抗原
- SIRPA (Signal-Regulatory Protein alpha (SIRPA))
- 别名
- SIRPA (SIRPA 产品)
- 别名
- BIT antibody, CD172A antibody, MFR antibody, MYD-1 antibody, P84 antibody, PTPNS1 antibody, SHPS1 antibody, SIRP antibody, SIRPA antibody, SIRP-A1 antibody, SIRP-B1 antibody, AI835480 antibody, Bit antibody, CD172a antibody, Ptpns1 antibody, SHP-1 antibody, SHPS-1 antibody, swc3 antibody, signal regulatory protein alpha antibody, myeloperoxidase antibody, signal-regulatory protein alpha antibody, tyrosine-protein phosphatase non-receptor type substrate 1 antibody, SIRPA antibody, MPO antibody, LOC458039 antibody, LOC100400378 antibody, LOC100590224 antibody, Sirpa antibody
- 背景
- The protein encoded by this gene is a member of the signal-regulatory-protein (SIRP) family, and also belongs to the immunoglobulin superfamily. SIRP family members are receptor-type transmembrane glycoproteins known to be involved in the negative regulation of receptor tyrosine kinase-coupled signaling processes. This protein can be phosphorylated by tyrosine kinases. The phospho-tyrosine residues of this PTP have been shown to recruit SH2 domain containing tyrosine phosphatases (PTP), and serve as substrates of PTPs. This protein was found to participate in signal transduction mediated by various growth factor receptors. CD47 has been demonstrated to be a ligand for this receptor protein. This gene and its product share very high similarity with several other members of the SIRP family. These related genes are located in close proximity to each other on chromosome 20p13. Multiple alternatively spliced transcript variants have been determined for this gene.,SIRPA,BIT,CD172A,MFR,MYD-1,P84,PTPNS1,SHPS1,SIRP,Signal Transduction,Cell Biology & Developmental Biology,Cell Adhesion,Immunology & Inflammation,CD markers,Neuroscience,Cell Type Marker,Cardiovascular,Neuron marker,Synapse marker,SIRPA
- 分子量
- 54 kDa/55 kDa
- 基因ID
- 140885
- UniProt
- P78324
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