SIGLEC12 抗体 (AA 20-210)
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- 抗原 See all SIGLEC12 抗体
- SIGLEC12 (Sialic Acid Binding Ig-Like Lectin 12 (SIGLEC12))
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抗原表位
- AA 20-210
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适用
- 人
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This SIGLEC12 antibody is un-conjugated
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应用范围
- Western Blotting (WB)
- 序列
- EQKDYLLTMQ KSVTVQEGLC VSVLCSFSYP QNGWTASDPV HGYWFRAGDH VSRNIPVATN NPARAVQEET RDRFHLLGDP QNKDCTLSIR DTRESDAGTY VFCVERGNMK WNYKYDQLSV NVTASQDLLS RYRLEVPESV TVQEGLCVSV PCSVLYPHYN WTASSPVYGS WFKEGADIPW DIPVATNTPS G
- 交叉反应
- 小鼠
- 产品特性
- Polyclonal Antibodies
- 免疫原
- Recombinant fusion protein containing a sequence corresponding to amino acids 20-210 of human SIGLEC12 (NP_443729.1).
- 亚型
- IgG
- Top Product
- Discover our top product SIGLEC12 Primary Antibody
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- 应用备注
- WB,1:500 - 1:2000
- 说明
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HIGH QUALITY
- 限制
- 仅限研究用
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- 状态
- Liquid
- 缓冲液
- PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- -20 °C
- 储存方法
- Store at -20°C. Avoid freeze / thaw cycles.
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- 抗原
- SIGLEC12 (Sialic Acid Binding Ig-Like Lectin 12 (SIGLEC12))
- 别名
- SIGLEC12 (SIGLEC12 产品)
- 别名
- S2V antibody, SIGLECL1 antibody, SLG antibody, Siglec-XII antibody, sialic acid binding Ig like lectin 12 (gene/pseudogene) antibody, sialic acid binding Ig like lectin 12 antibody, sialic acid binding Ig-like lectin 12 antibody, SIGLEC12 antibody
- 背景
- Sialic acid-binding immunoglobulin-like lectins (SIGLECs) are a family of cell surface proteins belonging to the immunoglobulin superfamily. They mediate protein-carbohydrate interactions by selectively binding to different sialic acid moieties present on glycolipids and glycoproteins. This gene encodes a member of the SIGLEC3-like subfamily of SIGLECs. Members of this subfamily are characterized by an extracellular V-set immunoglobulin-like domain followed by two C2-set immunoglobulin-like domains, and the cytoplasmic tyrosine-based motifs ITIM and SLAM-like. The encoded protein, upon tyrosine phosphorylation, has been shown to recruit the Src homology 2 domain-containing protein-tyrosine phosphatases SHP1 and SHP2. It has been suggested that the protein is involved in the negative regulation of macrophage signaling by functioning as an inhibitory receptor. This gene is located in a cluster with other SIGLEC3-like genes on 19q13.4. Alternative splicing results in multiple transcript variants.,SIGLEC12,S2V,SIGLECL1,SLG,Siglec-XII,Immunology & Inflammation,Cell Intrinsic Innate Immunity Signaling Pathway,SIGLEC12
- 分子量
- 51 kDa/64 kDa
- 基因ID
- 89858
- UniProt
- Q96PQ1
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