SAV1 抗体 (AA 1-210)
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- 抗原 See all SAV1 抗体
- SAV1 (Salvador Homolog 1 (SAV1))
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抗原表位
- AA 1-210
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适用
- 人
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This SAV1 antibody is un-conjugated
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应用范围
- Western Blotting (WB)
- 序列
- MLSRKKTKNE VSKPAEVQGK YVKKETSPLL RNLMPSFIRH GPTIPRRTDI CLPDSSPNAF STSGDVVSRN QSFLRTPIQR TPHEIMRRES NRLSAPSYLA RSLADVPREY GSSQSFVTEV SFAVENGDSG SRYYYSDNFF DGQRKRPLGD RAHEDYRYYE YNHDLFQRMP QNQGRHASGI GRVAATSLGN LTNHGSEDLP LPPGWSVDWT
- 交叉反应
- 人, 小鼠
- 产品特性
- Polyclonal Antibodies
- 免疫原
- Recombinant fusion protein containing a sequence corresponding to amino acids 1-210 of human SAV1 (NP_068590.1).
- 亚型
- IgG
- Top Product
- Discover our top product SAV1 Primary Antibody
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- 应用备注
- WB,1:1000 - 1:4000
- 说明
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HIGH QUALITY
- 限制
- 仅限研究用
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- 状态
- Liquid
- 缓冲液
- PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- -20 °C
- 储存方法
- Store at -20°C. Avoid freeze / thaw cycles.
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- 抗原
- SAV1 (Salvador Homolog 1 (SAV1))
- 别名
- SAV1 (SAV1 产品)
- 别名
- SAV antibody, WW45 antibody, WWP4 antibody, 1700040G09Rik antibody, Salv antibody, Sav antibody, Wwp3 antibody, Wwp4 antibody, salvador family WW domain containing protein 1 antibody, salvador family WW domain containing 1 antibody, SAV1 antibody, Sav1 antibody
- 背景
- WW domain-containing proteins are found in all eukaryotes and play an important role in the regulation of a wide variety of cellular functions such as protein degradation, transcription, and RNA splicing. This gene encodes a protein with two WW domains, a SARAH domain, and a coiled-coil region and is ubiquitously expressed in adult tissues. This protein binds to MST1 (mammalian sterile 20-like kinase 1) and promotes MST1-induced apoptosis. It has also been shown to bind to HAX1 (hematopoietic cell-specific protein 1 (HS1)-associated protein X-1) and to attenuate the anti-apoptotic effects of HAX1. Studies in human and mouse suggest this gene acts as a tumor suppressor.,SAV1,SAV,WW45,WWP4,Signal Transduction,Kinase,Cell Biology & Developmental Biology,Hippo Signaling Pathway,SAV1
- 分子量
- 44 kDa
- 基因ID
- 60485
- UniProt
- Q9H4B6
- 途径
- Stem Cell Maintenance
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