电话:
+86 (0512) 65829739
传真:
+86 (010) 6788 5057
电子邮件:
orders@antibodies-online.cn

SIRT1 抗体 (AA 456-555)

SIRT1 适用: 人 WB, IF, IHC (p), EIA 宿主: 小鼠 Monoclonal 7B7 unconjugated
产品编号 ABIN614713
发货至: 中国
  • 抗原 See all SIRT1 抗体
    SIRT1 (Sirtuin 1 (SIRT1))
    抗原表位
    • 31
    • 16
    • 16
    • 8
    • 8
    • 6
    • 6
    • 6
    • 5
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 456-555
    适用
    • 145
    • 88
    • 60
    • 34
    • 5
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    宿主
    • 130
    • 19
    • 2
    • 2
    • 1
    小鼠
    克隆类型
    • 118
    • 36
    单克隆
    标记
    • 64
    • 13
    • 10
    • 4
    • 4
    • 4
    • 4
    • 4
    • 4
    • 4
    • 4
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 1
    • 1
    This SIRT1 antibody is un-conjugated
    应用范围
    • 115
    • 50
    • 47
    • 41
    • 39
    • 35
    • 22
    • 21
    • 16
    • 13
    • 9
    • 4
    • 3
    • 3
    • 2
    • 1
    • 1
    • 1
    Western Blotting (WB), Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Enzyme Immunoassay (EIA)
    特异性
    This antibody reacts to Sirtuin-1 (SIRT1).
    纯化方法
    Protein A Chromatography
    免疫原
    Recombinant protein, SIRT1 (AAH12499, 456 a.a. ~ 555 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa. Genename: SIRT1
    克隆位点
    7B7
    亚型
    IgG1
    Top Product
    Discover our top product SIRT1 Primary Antibody
  • 应用备注
    Optimal working dilution should be determined by the investigator.
    限制
    仅限研究用
  • 缓冲液
    PBS, pH 7.2
    注意事项
    Avoid repeated freezing and thawing.
    储存条件
    4 °C/-20 °C
    储存方法
    Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
  • 抗原
    SIRT1 (Sirtuin 1 (SIRT1))
    别名
    SIRT1 (SIRT1 产品)
    别名
    sirtuin 1 antibody, AA673258 antibody, SIR2L1 antibody, Sir2 antibody, Sir2a antibody, Sir2alpha antibody, sir2l1 antibody, sirtuin antibody, SIR2 antibody, sirtuin 1 antibody, sirtuin 1 L homeolog antibody, SIRT1 antibody, SRT1 antibody, Sirt1 antibody, sirt1.L antibody
    背景
    The SIRT family of genes are highly conserved from prokaryotes to eukaryotes and are involved in diverse processes including transcriptional regulation, cell cycle progression, DNA damage repair and aging. Sirtuins utilize NAD+ as a substrate to catalyze deacetylation of specific acetylated protein and histones. SIRT1 has been shown to be induced by caloric restriction (CR) in several tissues and SIRT1 mediated deacetylase activity attenuates B-amyloid content in the brain during CR. SIRT1 also regulates the p53-dependent DNA damage response pathway by binding to and deacetylating p53.Synonyms: NAD-dependent deacetylase sirtuin-1, S. cerevisiae, SIR2-like protein 1, SIR2L1, SIR2alpha, SIRT-1, homolog) 1, sirtuin (silent mating type information regulation 2, sirtuin 1, sirtuin type 1, sirtuin-1
    基因ID
    23411
    NCBI登录号
    NP_001135970
    UniProt
    Q96EB6
    途径
    MAPK Pathway, Intracellular Steroid Hormone Receptor Signaling Pathway, Regulation of Intracellular Steroid Hormone Receptor Signaling, Carbohydrate Homeostasis, Positive Regulation of Endopeptidase Activity, Regulation of Carbohydrate Metabolic Process, Positive Regulation of Response to DNA Damage Stimulus, Negative Regulation of intrinsic apoptotic Signaling
You are here:
客服