AGS2 antibody, DLEU8 antibody, 1110019N06Rik antibody, 2610207P08Rik antibody, Dleu8 antibody, ribonuclease H2 subunit B antibody, ribonuclease H2, subunit B antibody, ribonuclease H2 subunit B L homeolog antibody, RNASEH2B antibody, Rnaseh2b antibody, rnaseh2b.L antibody
背景
RNase H2 is composed of a single catalytic subunit (A) and two non-catalytic subunits (B and C) and specifically degrades the RNA of RNA:DNA hybrids. The protein encoded by this gene is the non-catalytic B subunit of RNase H2, which is thought to play a role in DNA replication. Multiple transcript variants encoding different isoforms have been found for this gene. Defects in this gene are a cause of Aicardi-Goutieres syndrome type 2 (AGS2).,RNASEH2B,AGS2,DLEU8,Epigenetics & Nuclear Signaling,RNASEH2B