RICTOR and MTOR (FRAP1, MIM 601231) are components of a protein complex that integrates nutrient- and growth factor-derived signals to regulate cell growth (Sarbassov et al., 2004 [PubMed 15268862]).[supplied by OMIM, Mar 2008],RICTOR,AVO3,PIA,hAVO3,Epigenetics & Nuclear Signaling,Translation Control,Regulation of eIF4 and p70 S6 Kinase,Signal Transduction,PI3K-Akt Signaling Pathway,mTOR Signaling Pathway,Cell Biology & Developmental Biology,Cell Cycle,Cell cycle inhibitors,Endocrine & Metabolism,Insulin Receptor Signaling Pathway,Immunology & Inflammation,RICTOR