A2BP1 抗体 (AA 1-130)
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北京 101111
Quick Overview for A2BP1 抗体 (AA 1-130) (ABIN6146754)
抗原
See all A2BP1 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 1-130
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序列
- MLASQGVLLH PYGVPMIVPA APYLPGLIQG NQEAAAAPDT MAQPYASAQF APPQNGIPAE YTAPHPHPAP EYTGQTTVPE HTLNLYPPAQ THSEQSPADT SAQTVSGTAT QTDDAAPTDG QPQTQPSENT
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交叉反应
- 人, 小鼠, 大鼠
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产品特性
- Polyclonal Antibodies
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免疫原
- Recombinant fusion protein containing a sequence corresponding to amino acids 1-130 of human RBFOX1 (NP_665900.1).
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亚型
- IgG
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应用备注
- WB,1:500 - 1:2000,IHC,1:100 - 1:200
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Store at -20°C. Avoid freeze / thaw cycles.
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- A2BP1 (Ataxin 2-Binding Protein 1 (A2BP1))
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别名
- RBFOX1
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背景
- The Fox-1 family of RNA-binding proteins is evolutionarily conserved, and regulates tissue-specific alternative splicing in metazoa. Fox-1 recognizes a (U)GCAUG stretch in regulated exons or in flanking introns. The protein binds to the C-terminus of ataxin-2 and may contribute to the restricted pathology of spinocerebellar ataxia type 2 (SCA2). Ataxin-2 is the product of the SCA2 gene which causes familial neurodegenerative diseases. Fox-1 and ataxin-2 are both localized in the trans-Golgi network. Several alternatively spliced transcript variants encoding different isoforms have been found for this gene.,RBFOX1,2BP1,A2BP1,FOX-1,FOX1,HRNBP1,Epigenetics & Nuclear Signaling,Cell Biology & Developmental Biology,Neuroscience,Neurodegenerative Diseases,RBFOX1
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分子量
- 40 kDa/42 kDa/44 kDa
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基因ID
- 54715
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UniProt
- Q9NWB1
抗原
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