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FAK 抗体 (AA 700-800)

Name: FAK 抗体 (AA 700-800)
Brand: antibodies-online
SKU: ABIN6146423
Availability: OutOfStock

PTK2 适用: 人 WB, IHC, IF, IP 宿主: 兔 Polyclonal unconjugated

Western blot analysis of extracts of various cell lines, using PTK2 antibody. (FAK 抗体 (AA 700-800))

Immunofluorescence analysis of NIH/3T3 cells using FAK Rabbit pAb (ABIN6134667, ABIN6146423, ABIN6146425 and ABIN6215105) at dilution of 1:100 (40x lens). (FAK 抗体 (AA 700-800))

Immunohistochemistry of paraffin-embedded human colon using PTK2 antibody. (FAK 抗体 (AA 700-800))

IHC (p)

Immunofluorescence analysis of HeLa cells using PTK2 antibody. (FAK 抗体 (AA 700-800))

Immunofluorescence analysis of RAW264. (FAK 抗体 (AA 700-800))

Immunofluorescence analysis of PC12 cells using PTK2 antibody. (FAK 抗体 (AA 700-800))

Immunohistochemistry of paraffin-embedded human stomach using PTK2 antibody. (FAK 抗体 (AA 700-800))

IHC (p)

7 images

(1 reference)

产品编号 ABIN6146423

发货至: 中国

Datasheet as PDF

Key Features
- High quality FAK Primary Antibody for the detection of PTK2.
- Reliable product with high standard validation data
抗原 See all FAK (PTK2) 抗体

FAK (PTK2) (PTK2 Protein tyrosine Kinase 2 (PTK2))
抗原表位
43

35

34

29

28

22

22

18

16

16

11

11

8

7

6

6

5

5

4

3

3

3

3

3

2

2

2

2

2

2

2

2

2

2

2

2

2

2

2

2

2

2

2

2

2

2

1

1

1

1
AA 700-800
适用
350

305

232

21

21

17

16

11

8

6

6

4

3

3

2

1

1

1

1

1
人
宿主
362

17

3

2

1

1
兔
Compatible Secondaries
克隆类型
358

28
多克隆
标记
166

19

17

13

10

10

10

10

10

10

10

10

10

10

10

10

8

8

8

8

8

8

2

1
This FAK antibody is un-conjugated
应用范围
301

134

133

122

119

70

66

44

31

26

22

4

2

2
Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF), Immunoprecipitation (IP)

序列

TVSWDSGGSD EAPPKPSRPG YPSPRSSEGF YPSPQHMVQT NHYQVSGYPG SHGITAMAGS IYPGQASLLD QTDSWNHRPQ EIAMWQPNVE DSTVLDLRGI G

交叉反应

人, 小鼠, 大鼠

产品特性

Polyclonal Antibodies

免疫原

A synthetic peptide corresponding to a sequence within amino acids 700-800 of human FAK (NP_722560.1).

亚型

IgG

Top Product

Discover our top product PTK2 Primary Antibody

Product Specific Information

What can the FAK Antibody ABIN6146423 be used for?

This polyclonal FAK Antibody detects FAK. The FAK Antibody has been validated for various applications and can be used for the detection of FAK and derivatives by Western Blotting, Immunohistochemistry, Immunofluorescence, Immunoprecipitation.

What validation data is available for this FAK Antibody?

The Primary Antibody is referenced in 1 publications and is characterized by a proven, very high reliability. It has currently 7 product images that show its performance in a variety of applications. The product is currently available in 20 μL, 100 μL quantities. FAK Antibody for the detection of FAK and derivatives.

What is the function of FAK?

This gene encodes a cytoplasmic protein tyrosine kinase which is found concentrated in the focal adhesions that form between cells growing in the presence of extracellular matrix constituents. The encoded protein is a member of the FAK subfamily of protein tyrosine kinases but lacks significant sequence similarity to kinases from other subfamilies. Activation of this gene may be an important early step in cell growth and intracellular signal transduction pathways triggered in response to certain neural peptides or to cell interactions with the extracellular matrix. Several transcript variants encoding different isoforms have been found for this gene, but the full-length natures of only three of them have been determined. [provided by RefSeq, Dec 2010].
anti-PTK2 Protein tyrosine Kinase 2 (PTK2) (pTyr397) antibody
PTK2 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC, IF, ICC 宿主: 兔 Polyclonal unconjugated

anti-PTK2 Protein tyrosine Kinase 2 (PTK2) (AA 798-1041) antibody
PTK2 适用: 人 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated

anti-PTK2 Protein tyrosine Kinase 2 (PTK2) (AA 355-490) antibody
PTK2 适用: 人 WB, ELISA, IP, PLA 宿主: 小鼠 Monoclonal 2C3 unconjugated

anti-PTK2 Protein tyrosine Kinase 2 (PTK2) (pTyr576) antibody
PTK2 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC, IF, ICC 宿主: 兔 Polyclonal unconjugated

anti-PTK2 Protein tyrosine Kinase 2 (PTK2) (AA 396-423) antibody
PTK2 适用: 人 WB, IF, FACS, IHC (p) 宿主: 兔 Polyclonal RB20775 unconjugated

anti-PTK2 Protein tyrosine Kinase 2 (PTK2) (AA 1-680) antibody
PTK2 适用: 人 WB, PLA 宿主: 兔 Polyclonal unconjugated

anti-PTK2 Protein tyrosine Kinase 2 (PTK2) (pTyr861) antibody
PTK2 适用: 人, 小鼠, 大鼠 WB, ELISA, IF, ICC 宿主: 兔 Polyclonal unconjugated

anti-PTK2 Protein tyrosine Kinase 2 (PTK2) antibody
PTK2 适用: 人 WB, ELISA, IHC, ICC 宿主: 小鼠 Monoclonal 10H7 unconjugated

anti-PTK2 Protein tyrosine Kinase 2 (PTK2) antibody
PTK2 适用: 人 ELISA, FACS, ICC 宿主: 小鼠 Monoclonal 10H7E9 unconjugated

anti-PTK2 Protein tyrosine Kinase 2 (PTK2) (C-Term) antibody
PTK2 适用: 人 WB, IF, IHC (p), ICC 宿主: 兔 Polyclonal unconjugated

应用备注

WB,1:500 - 1:2000,IHC,1:50 - 1:200,IF,1:50 - 1:200,IP,1:50 - 1:100

限制

仅限研究用
状态

Liquid

缓冲液

PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

储存液

Sodium azide

注意事项

This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

储存条件

-20 °C

储存方法

Store at -20°C. Avoid freeze / thaw cycles.
Shen, Sun, Sun, Li, Wu, Li, Chen, Liu, Cui, Zhou: "ARRDC3 suppresses colorectal cancer progression through destabilizing the oncoprotein YAP." in: FEBS letters, Vol. 592, Issue 4, pp. 599-609, (2019) (PubMed).
抗原

FAK (PTK2) (PTK2 Protein tyrosine Kinase 2 (PTK2))

别名

PTK2 (PTK2 产品)

别名

FADK antibody, FAK antibody, FAK1 antibody, FRNK antibody, PPP1R71 antibody, p125FAK antibody, pp125FAK antibody, PTK2 antibody, Fadk antibody, mKIAA4203 antibody, fak antibody, fak1a antibody, ptk2 antibody, ptk2a antibody, wu:fa18c04 antibody, zgc:66114 antibody, CG10023 antibody, CT28129 antibody, DFAK antibody, DFak antibody, DFak56 antibody, Dfak antibody, Dfak56 antibody, DmFAK antibody, Dmel\\CG10023 antibody, Fak56 antibody, Fak56D antibody, fak56 antibody, protein tyrosine kinase 2 antibody, protein tyrosine kinase 2 L homeolog antibody, PTK2 protein tyrosine kinase 2 antibody, protein tyrosine kinase 2ab antibody, Focal adhesion kinase antibody, PTK2 antibody, ptk2.L antibody, Ptk2 antibody, ptk2ab antibody, Fak antibody

背景

This gene encodes a cytoplasmic protein tyrosine kinase which is found concentrated in the focal adhesions that form between cells growing in the presence of extracellular matrix constituents. The encoded protein is a member of the FAK subfamily of protein tyrosine kinases but lacks significant sequence similarity to kinases from other subfamilies. Activation of this gene may be an important early step in cell growth and intracellular signal transduction pathways triggered in response to certain neural peptides or to cell interactions with the extracellular matrix. Several transcript variants encoding different isoforms have been found for this gene.,FADK,FAK,FAK1,FRNK,PPP1R71,p125FAK,pp125FAK,PTK2,Cancer,Signal Transduction,G protein signaling,G2/M DNA Damage Checkpoint,Kinase,Tyrosine kinases,PI3K-Akt Signaling Pathway,ErbB-HER Signaling Pathway,MAPK-Erk Signaling Pathway,Cell Biology & Developmental Biology,Apoptosis,Cytoskeleton,Actins,Extracellular Matrix,Immunology & Inflammation,Cardiovascular,Angiogenesis,PTK2

分子量

39 kDa/48 kDa/63 kDa/99 kDa/114 kDa/119 kDa/120 kDa

基因ID

5747

UniProt

Q05397

途径

Response to Growth Hormone Stimulus, CXCR4-mediated Signaling Events, Smooth Muscle Cell Migration, Signaling of Hepatocyte Growth Factor Receptor, VEGF Signaling