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PKC zeta 抗体 (AA 453-592)

PRKCZ 适用: 人 WB, IF 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN6146211
发货至: 中国
  • 抗原 See all PKC zeta (PRKCZ) 抗体
    PKC zeta (PRKCZ) (Protein Kinase C, zeta (PRKCZ))
    抗原表位
    • 35
    • 27
    • 13
    • 11
    • 8
    • 6
    • 5
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
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    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
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    AA 453-592
    适用
    • 111
    • 63
    • 41
    • 9
    • 6
    • 5
    • 3
    • 3
    • 3
    • 2
    • 1
    • 1
    • 1
    宿主
    • 122
    • 3
    • 1
    克隆类型
    • 113
    • 13
    多克隆
    标记
    • 57
    • 9
    • 8
    • 6
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    This PKC zeta antibody is un-conjugated
    应用范围
    • 95
    • 54
    • 33
    • 26
    • 26
    • 20
    • 19
    • 9
    • 7
    • 6
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    Western Blotting (WB), Immunofluorescence (IF)
    序列
    IITDNPDMNT EDYLFQVILE KPIRIPRFLS VKASHVLKGF LNKDPKERLG CRPQTGFSDI KSHAFFRSID WDLLEKKQAL PPFQPQITDD YGLDNFDTQF TSEPVQLTPD DEDAIKRIDQ SEFEGFEYIN PLLLSTEESV
    交叉反应
    人, 小鼠, 大鼠
    产品特性
    Polyclonal Antibodies
    免疫原
    Recombinant fusion protein containing a sequence corresponding to amino acids 453-592 of human PKC zeta (NP_002735.3).
    亚型
    IgG
    Top Product
    Discover our top product PRKCZ Primary Antibody
  • 应用备注
    WB,1:500 - 1:1000,IF,1:50 - 1:200
    说明

    HIGH QUALITY

    限制
    仅限研究用
  • 状态
    Liquid
    缓冲液
    PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    -20 °C
    储存方法
    Store at -20°C. Avoid freeze / thaw cycles.
  • 抗原
    PKC zeta (PRKCZ) (Protein Kinase C, zeta (PRKCZ))
    别名
    PRKCZ (PRKCZ 产品)
    别名
    TPKC antibody, PKCzeta antibody, prkcz-A antibody, pkc-zeta antibody, PRKCZ antibody, pkc2 antibody, PKC-ZETA antibody, PKC2 antibody, AI098070 antibody, C80388 antibody, Pkcz antibody, R74924 antibody, aPKCzeta antibody, zetaPKC antibody, 14-3-3-zetaisoform antibody, r14-3-3 antibody, pkcz antibody, si:ch211-150o23.4 antibody, protein kinase C zeta L homeolog antibody, protein kinase C zeta antibody, protein kinase C, zeta antibody, prkcz.L antibody, PRKCZ antibody, prkcz antibody, Prkcz antibody
    背景
    Protein kinase C (PKC) zeta is a member of the PKC family of serine/threonine kinases which are involved in a variety of cellular processes such as proliferation, differentiation and secretion. Unlike the classical PKC isoenzymes which are calcium-dependent, PKC zeta exhibits a kinase activity which is independent of calcium and diacylglycerol but not of phosphatidylserine. Furthermore, it is insensitive to typical PKC inhibitors and cannot be activated by phorbol ester. Unlike the classical PKC isoenzymes, it has only a single zinc finger module. These structural and biochemical properties indicate that the zeta subspecies is related to, but distinct from other isoenzymes of PKC. Alternative splicing results in multiple transcript variants encoding different isoforms.,PRKCZ,PKC-ZETA,PKC2,Signal Transduction,G protein signaling,G2/M DNA Damage Checkpoint,Kinase,Serine/threonine kinases,Phospholipase Signaling Pathway,Protein Kinase C Signaling Pathway,ErbB-HER Signaling Pathway,MAPK-Erk Signaling Pathway,Cell Biology & Developmental Biology,Apoptosis,Mitochondrial Control of Apoptosis,Inhibition of Apoptosis,TGF-b-Smad Signaling Pathway,Endocrine & Metabolism,Insulin Receptor Signaling Pathway,Immunology & Inflammation,B Cell Receptor Signaling Pathway,NF-kB Signaling Pathway,PRKCZ
    分子量
    46 kDa/56 kDa/67 kDa
    基因ID
    5590
    UniProt
    Q05513
    途径
    NF-kappaB Signaling, RTK signaling, Myometrial Relaxation and Contraction, Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, Synaptic Membrane, Production of Molecular Mediator of Immune Response, CXCR4-mediated Signaling Events, Thromboxane A2 Receptor Signaling
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