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PPP1R12A 抗体 (AA 1-200)

Name: PPP1R12A 抗体 (AA 1-200)
Brand: antibodies-online
SKU: ABIN6146059
Availability: OutOfStock

PPP1R12A 适用: 人 WB, IF, IP 宿主: 兔 Polyclonal unconjugated

Western blot analysis of extracts of various cell lines, using PPP1R12A antibody. (PPP1R12A 抗体 (AA 1-200))

Immunofluorescence analysis of U2OS cells using PPP1R12A Rabbit pAb (ABIN6128260, ABIN6146059, ABIN6146061 and ABIN6213896) at dilution of 1:100 (40x lens). (PPP1R12A 抗体 (AA 1-200))

Immunofluorescence analysis of HeLa cells using PPP1R12A Rabbit pAb (ABIN6128260, ABIN6146059, ABIN6146061 and ABIN6213896) at dilution of 1:100 (40x lens). (PPP1R12A 抗体 (AA 1-200))

Immunofluorescence analysis of NIH/3T3 cells using PPP1R12A Rabbit pAb (ABIN6128260, ABIN6146059, ABIN6146061 and ABIN6213896) at dilution of 1:100 (40x lens). (PPP1R12A 抗体 (AA 1-200))

Immunofluorescence analysis of PC-12 cells using PPP1R12A Rabbit pAb (ABIN6128260, ABIN6146059, ABIN6146061 and ABIN6213896) at dilution of 1:100 (40x lens). (PPP1R12A 抗体 (AA 1-200))

Immunoprecipitation analysis of 200 μg extracts of HeLa cells, using 3 μg PPP1R12A antibody (ABIN6128260, ABIN6146059, ABIN6146061 and ABIN6213896). (PPP1R12A 抗体 (AA 1-200))

6 images

产品编号 ABIN6146059

发货至: 中国

Datasheet as PDF

抗原 See all PPP1R12A 抗体

PPP1R12A (Myosin Phosphatase, Target Subunit 1 (PPP1R12A))
抗原表位
26

23

7

7

7

7

4

4

3

2

2

2

2

2

2

2

2

2

2

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1
AA 1-200
适用
92

82

66

6

5

4

4

3

3

3

3

3

2

1
人
宿主
114

1
兔
Compatible Secondaries
克隆类型
115
多克隆
标记
52

7

5

5

5

5

5

5

2

2

2

2

2

2

2

2

2

2

2

2

2
This PPP1R12A antibody is un-conjugated
应用范围
59

27

26

26

20

13

6

6

3

2

1

1
Western Blotting (WB), Immunofluorescence (IF), Immunoprecipitation (IP)

序列

MKMADAKQKR NEQLKRWIGS ETDLEPPVVK RQKTKVKFDD GAVFLAACSS GDTDEVLKLL HRGADINYAN VDGLTALHQA CIDDNVDMVK FLVENGANIN QPDNEGWIPL HAAASCGYLD IAEFLIGQGA HVGAVNSEGD TPLDIAEEEA MEELLQNEVN RQGVDIEAAR KEEERIMLRD ARQWLNSGHI NDVRHAKSGG

交叉反应

人, 小鼠, 大鼠

产品特性

Polyclonal Antibodies

免疫原

Recombinant fusion protein containing a sequence corresponding to amino acids 1-200 of human PPP1R12A (NP_002471.1).

亚型

IgG

Top Product

Discover our top product PPP1R12A Primary Antibody
anti-Myosin Phosphatase, Target Subunit 1 (PPP1R12A) (C-Term) antibody
Verified PPP1R12A 适用: 人 ELISA, IHC, IF, FACS 宿主: 山羊 Polyclonal unconjugated

anti-Myosin Phosphatase, Target Subunit 1 (PPP1R12A) (AA 1-40), (N-Term) antibody
PPP1R12A 适用: 人, 小鼠 WB, IHC (p) 宿主: 兔 Polyclonal unconjugated

anti-Myosin Phosphatase, Target Subunit 1 (PPP1R12A) (C-Term) antibody
PPP1R12A 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated

anti-Myosin Phosphatase, Target Subunit 1 (PPP1R12A) (pThr696) antibody
PPP1R12A 适用: 人, 大鼠 WB, FACS 宿主: 兔 Polyclonal unconjugated

anti-Myosin Phosphatase, Target Subunit 1 (PPP1R12A) (pThr853) antibody
PPP1R12A 适用: 人 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated

anti-Myosin Phosphatase, Target Subunit 1 (PPP1R12A) (AA 481-514), (Ser507) antibody
PPP1R12A 适用: 人, 小鼠 WB 宿主: 兔 Polyclonal RB56872 unconjugated

anti-Myosin Phosphatase, Target Subunit 1 (PPP1R12A) (Thr103) antibody
PPP1R12A 适用: 人, 小鼠, 大鼠, 猴 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated

anti-Myosin Phosphatase, Target Subunit 1 (PPP1R12A) (pThr853) antibody
PPP1R12A 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated

anti-Myosin Phosphatase, Target Subunit 1 (PPP1R12A) (AA 710-970) antibody
PPP1R12A 适用: 人 WB, IHC 宿主: 兔 Polyclonal unconjugated

anti-Myosin Phosphatase, Target Subunit 1 (PPP1R12A) (pSer696) antibody
PPP1R12A 适用: 人, 小鼠, 大鼠, 小鸡, 斑马鱼, Pig WB, IHC, IF, IC 宿主: 兔 Polyclonal unconjugated

应用备注

WB,1:500 - 1:2000,IF,1:50 - 1:200,IP,1:50 - 1:100

说明

HIGH QUALITY

限制

仅限研究用
状态

Liquid

缓冲液

PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

储存液

Sodium azide

注意事项

This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

储存条件

-20 °C

储存方法

Store at -20°C. Avoid freeze / thaw cycles.
抗原

PPP1R12A (Myosin Phosphatase, Target Subunit 1 (PPP1R12A))

别名

PPP1R12A (PPP1R12A 产品)

别名

1200015F06Rik antibody, 5730577I22Rik antibody, AA792106 antibody, AV099298 antibody, D10Ertd625e antibody, Mypt1 antibody, M130 antibody, MBS antibody, MYPT1 antibody, M110 antibody, MBSP antibody, protein phosphatase 1, regulatory (inhibitor) subunit 12A antibody, protein phosphatase 1 regulatory subunit 12A antibody, protein phosphatase 1, regulatory subunit 12A antibody, Ppp1r12a antibody, PPP1R12A antibody

背景

Myosin phosphatase target subunit 1, which is also called the myosin-binding subunit of myosin phosphatase, is one of the subunits of myosin phosphatase. Myosin phosphatase regulates the interaction of actin and myosin downstream of the guanosine triphosphatase Rho. The small guanosine triphosphatase Rho is implicated in myosin light chain (MLC) phosphorylation, which results in contraction of smooth muscle and interaction of actin and myosin in nonmuscle cells. The guanosine triphosphate (GTP)-bound, active form of RhoA (GTP.RhoA) specifically interacted with the myosin-binding subunit (MBS) of myosin phosphatase, which regulates the extent of phosphorylation of MLC. Rho-associated kinase (Rho-kinase), which is activated by GTP. RhoA, phosphorylated MBS and consequently inactivated myosin phosphatase. Overexpression of RhoA or activated RhoA in NIH 3T3 cells increased phosphorylation of MBS and MLC. Thus, Rho appears to inhibit myosin phosphatase through the action of Rho-kinase. Several transcript variants encoding different isoforms have been found for this gene.,PPP1R12A,M130,MBS,MYPT1,MYPT1,Epigenetics & Nuclear Signaling,Signal Transduction,Kinase,Serine/threonine kinases,Cell Biology & Developmental Biology,Cell Cycle,Cytoskeleton,Motor Proteins,Actins,PPP1R12A

分子量

105 kDa/109 kDa/111 kDa/115 kDa

基因ID

4659

UniProt

O14974

途径

M Phase