POU2F3 antibody, zgc:136377 antibody, zgc:158534 antibody, Epoc-1 antibody, OCT-11 antibody, OCT11 antibody, OTF-11 antibody, PLA-1 antibody, PLA1 antibody, Skn-1a antibody, nrl-16 antibody, nrl16-A antibody, Oct-11a antibody, Oct11 antibody, Otf-11 antibody, Otf11 antibody, Skin antibody, Skin-1a antibody, Skn-li antibody, POU class 2 homeobox 3 antibody, POU class 2 homeobox 3 L homeolog antibody, POU domain, class 2, transcription factor 3 antibody, POU2F3 antibody, pou2f3 antibody, Pou2f3 antibody, pou2f3.L antibody
背景
This gene encodes a member of the POU domain family of transcription factors. POU domain transcription factors bind to a specific octamer DNA motif and regulate cell type-specific differentiation pathways. The encoded protein is primarily expressed in the epidermis, and plays a critical role in keratinocyte proliferation and differentiation. The encoded protein is also a candidate tumor suppressor protein, and aberrant promoter methylation of this gene may play a role in cervical cancer. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene.,POU2F3,Epoc-1,OCT-11,OCT11,OTF-11,PLA-1,PLA1,Skn-1a,Epigenetics & Nuclear Signaling,Transcription Factors,POU2F3