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NOXA 抗体 (AA 1-54)

PMAIP1 适用: 人 WB, IF 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN6145810
发货至: 中国
  • 抗原 See all NOXA (PMAIP1) 抗体
    NOXA (PMAIP1) (Phorbol-12-Myristate-13-Acetate-Induced Protein 1 (PMAIP1))
    抗原表位
    • 6
    • 3
    • 1
    • 1
    • 1
    • 1
    AA 1-54
    适用
    • 30
    • 4
    • 2
    宿主
    • 23
    • 6
    • 1
    • 1
    克隆类型
    • 18
    • 13
    多克隆
    标记
    • 13
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    This NOXA antibody is un-conjugated
    应用范围
    • 10
    • 10
    • 4
    • 3
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Western Blotting (WB), Immunofluorescence (IF)
    序列
    MPGKKARKNA QPSPARAPAE LEVECATQLR RFGDKLNFRQ KLLNLISKLF CSGT
    交叉反应
    人, 小鼠, 大鼠
    产品特性
    Polyclonal Antibodies
    免疫原
    A synthetic peptide corresponding to a sequence within amino acids 1-54 of human PMAIP1 (NP_066950.1).
    亚型
    IgG
  • 应用备注
    WB,1:500 - 1:2000,IF,1:50 - 1:200
    说明

    HIGH QUALITY

    限制
    仅限研究用
  • 状态
    Liquid
    缓冲液
    PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    -20 °C
    储存方法
    Store at -20°C. Avoid freeze / thaw cycles.
  • 抗原
    NOXA (PMAIP1) (Phorbol-12-Myristate-13-Acetate-Induced Protein 1 (PMAIP1))
    别名
    PMAIP1 (PMAIP1 产品)
    别名
    TN3 antibody, PMAIP1 antibody, zgc:162379 antibody, APR antibody, NOXA antibody, Noxa antibody, phorbol-12-myristate-13-acetate-induced protein 1 antibody, PMAIP1 antibody, pmaip1 antibody, Pmaip1 antibody
    背景
    Promotes activation of caspases and apoptosis. Promotes mitochondrial membrane changes and efflux of apoptogenic proteins from the mitochondria. Contributes to p53/TP53-dependent apoptosis after radiation exposure. Promotes proteasomal degradation of MCL1. Competes with BAK1 for binding to MCL1 and can displace BAK1 from its binding site on MCL1 (By similarity. Competes with BIM/BCL2L11 for binding to MCL1 and can displace BIM/BCL2L11 from its binding site on MCL1.,PMAIP1,APR,NOXA,Cancer,Invasion and Metastasis,Cell Biology & Developmental Biology,Apoptosis,Bcl 2 family,Mitochondrial Control of Apoptosis,Endocrine & Metabolism,PMAIP1
    分子量
    6 kDa/14 kDa
    基因ID
    5366
    UniProt
    Q13794
    途径
    p53 Pathway, Positive Regulation of Endopeptidase Activity, Regulation of Carbohydrate Metabolic Process, Positive Regulation of Response to DNA Damage Stimulus
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